Literature DB >> 27741404

The Language of Life.

Ann C Palmenberg1.   

Abstract

Science is our best current approximation of the way things work. You cannot do science unless you believe there is a discernable truth inherent to the arrangement of our tangible world. The problem is, we in our given time never know where exactly the asymptote lies or how far we are from it. My curiosity about the natural world is innate, but fate has variously gifted me with outstanding personal opportunities to indulge that curiosity through the study of viruses. To a woman of the boomer generation, professional paths were not always open-door, and to a certain extent they still aren't. Whether such points should now be viewed as obstacles or stepping stones is a matter of perspective. RNA viruses, and the multiple, seminal mentors who taught me their secrets, have defined my career. Some of their stories are told here as they dovetail with mine. If there is any unity to this, it would be a pursuit of the language of life, or sequence analysis, as taught to us by natural selection. The intent here is not a legacy but an example. Science is a beautiful fate.

Entities:  

Keywords:  RNA; autobiography; cardiovirus; fate; rhinovirus; sequence analysis

Mesh:

Substances:

Year:  2016        PMID: 27741404      PMCID: PMC5206909          DOI: 10.1146/annurev-virology-110615-035544

Source DB:  PubMed          Journal:  Annu Rev Virol        ISSN: 2327-056X            Impact factor:   10.431


  42 in total

1.  PREPARATIVE ELECTROPHORESIS OF PROTEINS IN ACRYLAMIDE GELS.

Authors:  J V MAIZEL
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

2.  How the American Society for Virology was founded.

Authors:  Wolfang K Joklik; Sidney E Grossberg
Journal:  Virology       Date:  2006-01-05       Impact factor: 3.616

3.  Prediction of three-dimensional models for foot-and-mouth disease virus and hepatitis A virus.

Authors:  M Luo; M G Rossmann; A C Palmenberg
Journal:  Virology       Date:  1988-10       Impact factor: 3.616

4.  The atomic structure of Mengo virus at 3.0 A resolution.

Authors:  M Luo; G Vriend; G Kamer; I Minor; E Arnold; M G Rossmann; U Boege; D G Scraba; G M Duke; A C Palmenberg
Journal:  Science       Date:  1987-01-09       Impact factor: 47.728

5.  Cell-free synthesis and processing of the proteins of poliovirus.

Authors:  D S Shih; C T Shih; O Kew; M Pallansch; R Rueckert; P Kaesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

6.  Gene order of encephalomyocarditis virus as determined by studies with pactamycin.

Authors:  B E Butterworth; R R Rueckert
Journal:  J Virol       Date:  1972-05       Impact factor: 5.103

7.  Synthesis of complementary strands of heterologous RNAs with Qbeta replicase.

Authors:  A Palmenberg; P Kaesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

8.  The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme.

Authors:  S Spiegelman; I Haruna; I B Holland; G Beaudreau; D Mills
Journal:  Proc Natl Acad Sci U S A       Date:  1965-09       Impact factor: 11.205

9.  Evidence for intramolecular self-cleavage of picornaviral replicase precursors.

Authors:  A C Palmenberg; R R Rueckert
Journal:  J Virol       Date:  1982-01       Impact factor: 5.103

10.  Leader-induced phosphorylation of nucleoporins correlates with nuclear trafficking inhibition by cardioviruses.

Authors:  Frederick W Porter; Ann C Palmenberg
Journal:  J Virol       Date:  2008-12-10       Impact factor: 5.103

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