Literature DB >> 27738623

INTRAMEDULLARY TUBERCULOMA OF THORACIC SPINAL CORD IN AN APPARENTLY HEALTHY NIGERIAN: CASE REPORT.

A S Yusuf1, N A Adeleke1, O M Babalola1, K W Wahab2, L O Oyebanji3, A B Ahmed1, H K Omokanye4.   

Abstract

Spinal intramedullary is an uncommon form of tuberculosis causing spinal cord injury in this environment. We report a case of thoracic intramedullary tuberculoma in an immunocompetent male Nigerian with negative screening for tuberculosis. He presented with 8 months history of back pain and 2 months history of progressive weakness in both lower limbs. Physical examination revealed a well-nourished man with spastic paraplegia. Chest radiograph and CT scan were normal but Magnetic resonance imaging (MRI) of the thoracolumbar region showed cord oedema and circumscribed intramedullary lesions at D12 and L1 levels with target sign. The patient was promptly prepared and had D12 and L1 laminectomy and posterior myelotomy with excision of the intramedullary lesion. Histology showed granulomatous lesion with central caseation in keeping with a tuberculoma. He was treated with a 4-drug antituberculous regimen with physiotherapy and he made complete neurological recovery 8 months post-operatively. Intramedullary tuberculoma should be considered in differential diagnosis of intramedullary tumors in this environment. Treatment with antituberculous drugs results in good outcome.

Entities:  

Keywords:  Good outcome; Immunocompetent patient; Intramedullary spinal tuberculoma

Year:  2015        PMID: 27738623      PMCID: PMC5020892     

Source DB:  PubMed          Journal:  J West Afr Coll Surg        ISSN: 2276-6944


  18 in total

1.  Demonstration of intramedullary tuberculomas by magnetic resonance imaging: a report of two cases.

Authors:  A Jena; A K Banerji; R P Tripathi; P K Gulati; R K Jain; S Khushu; M L Sapra
Journal:  Br J Radiol       Date:  1991-06       Impact factor: 3.039

Review 2.  Intramedullary tuberculomas of the spinal cord: case report and review.

Authors:  A H MacDonnell; R W Baird; M S Bronze
Journal:  Rev Infect Dis       Date:  1990 May-Jun

3.  Spinal intramedullary tuberculous lesion: medical management. Report of four cases.

Authors:  G P Rao
Journal:  J Neurosurg       Date:  2000-07       Impact factor: 5.115

4.  Tuberculomas presenting as isolated intrinsic brain stem masses.

Authors:  V Rajshekhar; M J Chandy
Journal:  Br J Neurosurg       Date:  1997-04       Impact factor: 1.596

5.  Intramedullary tuberculosis manifested as Brown-Sequard syndrome in a patient with systemic lupus erythematosus.

Authors:  W U Kim; S H Lee; B Y Shim; J K Min; Y S Hong; S H Park; C S Cho; C K Park; H Y Kim
Journal:  Lupus       Date:  2000       Impact factor: 2.911

6.  Intramedullary cervical tuberculoma: a case report with note on surgical management.

Authors:  Hong-Bin Ju; Dong-Ming Guo; Fan-Fan Chen
Journal:  Int Surg       Date:  2015-01

7.  Spinal tuberculosis: a diagnostic and management challenge.

Authors:  E S Nussbaum; G L Rockswold; T A Bergman; D L Erickson; E L Seljeskog
Journal:  J Neurosurg       Date:  1995-08       Impact factor: 5.115

8.  Concurrent intra-medullary and intra-cranial tuberculomas.

Authors:  M M Thacker; A I Puri
Journal:  J Postgrad Med       Date:  2004 Apr-Jun       Impact factor: 1.476

9.  Spinal cord compression due to primary intramedullary tuberculoma of the spinal cord presenting as paraplegia: A case report and literature review.

Authors:  Sudhansu Sekhar Mishra; Deepak Das; Srikanta Das; Itibrata Mohanta; Soubhagya Ranjan Tripathy
Journal:  Surg Neurol Int       Date:  2015-03-23

10.  A rare case of intramedullary tuberculoma: Complete resolution after medical treatment and role of magnetic resonance imaging in diagnosis and follow-up.

Authors:  Suresh Chidambaram Thirunavukarasu; Arunkumar Ramachandrappa
Journal:  Asian J Neurosurg       Date:  2012-10
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  2 in total

1.  Intramedullary Spinal Tuberculoma: An Uncommon Presentation of a Common Disorder.

Authors:  Samra Iftikhar; Nadeem Ijaz; Sidrah Iftikhar; Shandana Khan
Journal:  Cureus       Date:  2022-09-04

Review 2.  Spinal intramedullary tuberculoma following pulmonary tuberculosis: A case report and literature review.

Authors:  Guan-Chyuan Wang; Sheng-Wen Wu
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

  2 in total

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