Literature DB >> 27738369

Roland Kuhn-100th Birthday of an Innovator of Clinical Psychopharmacology.

Holger Steinberg1, Hubertus Himmerich1.   

Abstract

On the occasion of his 100th birthday this letter is to pay tribute to Swiss psychiatrist and psychopharmacologist Roland Kuhn (1912-2005), who established the antidepressant effects of imipramine starting in 1956. Since until now only monoaminergic-based antidepressants such as this substance found their way into psychopharmacological therapy, one can say that Kuhn established the lead antidepressant substance and has hence fundamentally changed clinical psychiatry and care for the mentally ill.

Entities:  

Keywords:  Roland Kuhn; antidepressants; history of pharmacopsychiatry

Year:  2012        PMID: 27738369      PMCID: PMC5044476     

Source DB:  PubMed          Journal:  Psychopharmacol Bull        ISSN: 0048-5764


  7 in total

1.  The treatment of depressive states with G 22355 (imipramine hydrochloride).

Authors:  R KUHN
Journal:  Am J Psychiatry       Date:  1958-11       Impact factor: 18.112

2.  [Treatment of depressive states with an iminodibenzyl derivative (G 22355)].

Authors:  R KUHN
Journal:  Schweiz Med Wochenschr       Date:  1957-08-31

Review 3.  Regulation of neurogenesis and gliogenesis by stress and antidepressant treatment.

Authors:  Mounira Banasr; Ronald S Duman
Journal:  CNS Neurol Disord Drug Targets       Date:  2007-10       Impact factor: 4.388

Review 4.  From synapse to nucleus: novel targets for treating depression.

Authors:  Herbert E Covington; Vincent Vialou; Eric J Nestler
Journal:  Neuropharmacology       Date:  2009-12-17       Impact factor: 5.250

Review 5.  The catecholamine hypothesis of affective disorders: a review of supporting evidence.

Authors:  J J Schildkraut
Journal:  Am J Psychiatry       Date:  1965-11       Impact factor: 18.112

Review 6.  The combined dexamethasone/CRH test as a potential surrogate marker in depression.

Authors:  Marcus Ising; Heike E Künzel; Elisabeth B Binder; Thomas Nickel; Sieglinde Modell; Florian Holsboer
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2005-07       Impact factor: 5.067

7.  Regulatory T cells increased while IL-1β decreased during antidepressant therapy.

Authors:  Hubertus Himmerich; Saša Milenović; Stephany Fulda; Birgit Plümäkers; Abigail J Sheldrick; Tanja M Michel; Tilo Kircher; Lothar Rink
Journal:  J Psychiatr Res       Date:  2010-04-21       Impact factor: 4.791

  7 in total
  1 in total

Review 1.  [Everyday transgressions of borderlines: the scandalization of clinical drug trials of the psychiatrist Roland Kuhn].

Authors:  Hanfried Helmchen
Journal:  Nervenarzt       Date:  2022-05-06       Impact factor: 1.214

  1 in total

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