| Literature DB >> 27736636 |
Daniel Sauter1, Frank Kirchhoff2.
Abstract
IFITMs inhibit various enveloped viral pathogens in vitro, but their relevance in vivo has remained unclear. In this issue of Cell Host & Microbe, Foster et al. (2016) show that IFITMs constitute a barrier to HIV-1 transmission and that escape from adaptive immune responses increases viral sensitivity to IFITM restriction.Entities:
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Year: 2016 PMID： 27736636 DOI： 10.1016/j.chom.2016.09.009
Source DB: PubMed Journal: Cell Host Microbe ISSN： 1931-3128 Impact factor: 21.023