Literature DB >> 27734248

FXR Agonists: From Bench to Bedside, a Guide for Clinicians.

Ahmad Samer Alawad1, Cynthia Levy2.   

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Year:  2016        PMID： 27734248     DOI： 10.1007/s10620-016-4334-8

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


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  45 in total

1.  Antiatherosclerotic effect of farnesoid X receptor.

Authors:  Andrea Mencarelli; Barbara Renga; Eleonora Distrutti; Stefano Fiorucci
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-11-21       Impact factor: 4.733

Review 2.  Orphan nuclear receptors--new ligands and new possibilities.

Authors:  B Blumberg; R M Evans
Journal:  Genes Dev       Date:  1998-10-15       Impact factor: 11.361

3.  Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice.

Authors:  Insook Kim; Keiichirou Morimura; Yatrik Shah; Qian Yang; Jerrold M Ward; Frank J Gonzalez
Journal:  Carcinogenesis       Date:  2006-12-20       Impact factor: 4.944

4.  Identification of a nuclear receptor for bile acids.

Authors:  M Makishima; A Y Okamoto; J J Repa; H Tu; R M Learned; A Luk; M V Hull; K D Lustig; D J Mangelsdorf; B Shan
Journal:  Science       Date:  1999-05-21       Impact factor: 47.728

Review 5.  Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis.

Authors:  Luciano Adorini; Mark Pruzanski; David Shapiro
Journal:  Drug Discov Today       Date:  2012-05-29       Impact factor: 7.851

6.  Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response.

Authors:  Yan-Dong Wang; Wei-Dong Chen; Meihua Wang; Donna Yu; Barry M Forman; Wendong Huang
Journal:  Hepatology       Date:  2008-11       Impact factor: 17.425

7.  Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease.

Authors:  Sunder Mudaliar; Robert R Henry; Arun J Sanyal; Linda Morrow; Hanns-Ulrich Marschall; Mark Kipnes; Luciano Adorini; Cathi I Sciacca; Paul Clopton; Erin Castelloe; Paul Dillon; Mark Pruzanski; David Shapiro
Journal:  Gastroenterology       Date:  2013-05-30       Impact factor: 22.682

8.  FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis.

Authors:  Serkan Kir; Sara A Beddow; Varman T Samuel; Paul Miller; Stephen F Previs; Kelly Suino-Powell; H Eric Xu; Gerald I Shulman; Steven A Kliewer; David J Mangelsdorf
Journal:  Science       Date:  2011-03-25       Impact factor: 47.728

9.  Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid.

Authors:  Gideon M Hirschfield; Andrew Mason; Velimir Luketic; Keith Lindor; Stuart C Gordon; Marlyn Mayo; Kris V Kowdley; Catherine Vincent; Henry C Bodhenheimer; Albert Parés; Michael Trauner; Hanns-Ulrich Marschall; Luciano Adorini; Cathi Sciacca; Tessa Beecher-Jones; Erin Castelloe; Olaf Böhm; David Shapiro
Journal:  Gastroenterology       Date:  2014-12-11       Impact factor: 22.682

10.  Upregulation of microRNA-122 by farnesoid X receptor suppresses the growth of hepatocellular carcinoma cells.

Authors:  Jialin He; Kai Zhao; Lu Zheng; Zhizhen Xu; Wei Gong; Shan Chen; Xiaodong Shen; Gang Huang; Min Gao; Yijun Zeng; Yan Zhang; Fengtian He
Journal:  Mol Cancer       Date:  2015-08-25       Impact factor: 27.401
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  9 in total

1.  Discovery of new FXR agonists based on 6-ECDCA binding properties by virtual screening and molecular docking.

Authors:  Antonella Giancristofaro; Arménio J M Barbosa; Alessandra Ammazzalorso; Pasquale Amoia; Barbara De Filippis; Marialuigia Fantacuzzi; Letizia Giampietro; Cristina Maccallini; Rosa Amoroso
Journal:  Medchemcomm       Date:  2018-07-04       Impact factor: 3.597

2.  Blinded evaluation of farnesoid X receptor (FXR) ligands binding using molecular docking and free energy calculations.

Authors:  Edithe Selwa; Eddy Elisée; Agustin Zavala; Bogdan I Iorga
Journal:  J Comput Aided Mol Des       Date:  2017-09-02       Impact factor: 3.686

Review 3.  NAFLD in children: new genes, new diagnostic modalities and new drugs.

Authors:  Valerio Nobili; Anna Alisi; Luca Valenti; Luca Miele; Ariel E Feldstein; Naim Alkhouri
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2019-07-05       Impact factor: 46.802

4.  Hypercholesterolemia Due to Lipoprotein X: Case Report and Thematic Review.

Authors:  Laura Kattah; Andrés Gómez; Sebastián Gutiérrez; Kathalina Puerto; Eiman D Moreno-Pallares; Andrés Jaramillo; Carlos O Mendivil
Journal:  Clin Med Insights Endocrinol Diabetes       Date:  2019-09-29

5.  Dysregulated bile acid receptor-mediated signaling and IL-17A induction are implicated in diet-associated hepatic health and cognitive function.

Authors:  Prasant Kumar Jena; Lili Sheng; Michelle Nguyen; Jacopo Di Lucente; Ying Hu; Yongchun Li; Izumi Maezawa; Lee-Way Jin; Yu-Jui Yvonne Wan
Journal:  Biomark Res       Date:  2020-11-06

6.  Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis.

Authors:  Tsuneyuki Miyazaki; Yohei Shirakami; Taku Mizutani; Akinori Maruta; Takayasu Ideta; Masaya Kubota; Hiroyasu Sakai; Takashi Ibuka; Salvatore Genovese; Serena Fiorito; Vito Alessandro Taddeo; Francesco Epifano; Takuji Tanaka; Masahito Shimizu
Journal:  Sci Rep       Date:  2021-01-12       Impact factor: 4.379

Review 7.  Meta-analysis and Consolidation of Farnesoid X Receptor Chromatin Immunoprecipitation Sequencing Data Across Different Species and Conditions.

Authors:  Emilian Jungwirth; Katrin Panzitt; Hanns-Ulrich Marschall; Gerhard G Thallinger; Martin Wagner
Journal:  Hepatol Commun       Date:  2021-07-01

Review 8.  Update on FXR Biology: Promising Therapeutic Target?

Authors:  Chang Yeob Han
Journal:  Int J Mol Sci       Date:  2018-07-16       Impact factor: 5.923

9.  Beneficial Activities of Alisma orientale Extract in a Western Diet-Induced Murine Non-Alcoholic Steatohepatitis and Related Fibrosis Model via Regulation of the Hepatic Adiponectin and Farnesoid X Receptor Pathways.

Authors:  Seung Ho Jeon; Eungyeong Jang; Geonha Park; Yeongae Lee; Young Pyo Jang; Kyung-Tae Lee; Kyung-Soo Inn; Jong Kil Lee; Jang-Hoon Lee
Journal:  Nutrients       Date:  2022-02-07       Impact factor: 5.717
  9 in total

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