Literature DB >> 27732582

Drug discovery: Chemical diversity targets malaria.

David A Fidock1.   

Abstract

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Year:  2016        PMID： 27732582     DOI： 10.1038/nature19481

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  9 in total

Review 1.  Malaria medicines: a glass half full?

Authors:  Timothy N C Wells; Rob Hooft van Huijsduijnen; Wesley C Van Voorhis
Journal:  Nat Rev Drug Discov       Date:  2015-05-22       Impact factor: 84.694

2.  Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.

Authors:  Nobutaka Kato; Eamon Comer; Tomoyo Sakata-Kato; Arvind Sharma; Manmohan Sharma; Micah Maetani; Jessica Bastien; Nicolas M Brancucci; Joshua A Bittker; Victoria Corey; David Clarke; Emily R Derbyshire; Gillian L Dornan; Sandra Duffy; Sean Eckley; Maurice A Itoe; Karin M J Koolen; Timothy A Lewis; Ping S Lui; Amanda K Lukens; Emily Lund; Sandra March; Elamaran Meibalan; Bennett C Meier; Jacob A McPhail; Branko Mitasev; Eli L Moss; Morgane Sayes; Yvonne Van Gessel; Mathias J Wawer; Takashi Yoshinaga; Anne-Marie Zeeman; Vicky M Avery; Sangeeta N Bhatia; John E Burke; Flaminia Catteruccia; Jon C Clardy; Paul A Clemons; Koen J Dechering; Jeremy R Duvall; Michael A Foley; Fabian Gusovsky; Clemens H M Kocken; Matthias Marti; Marshall L Morningstar; Benito Munoz; Daniel E Neafsey; Amit Sharma; Elizabeth A Winzeler; Dyann F Wirth; Christina A Scherer; Stuart L Schreiber
Journal:  Nature       Date:  2016-09-07       Impact factor: 49.962

3.  Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.

Authors:  Jason T Lowe; Maurice D Lee; Lakshmi B Akella; Emeline Davoine; Etienne J Donckele; Landon Durak; Jeremy R Duvall; Baudouin Gerard; Edward B Holson; Adrien Joliton; Sarathy Kesavan; Berenice C Lemercier; Haibo Liu; Jean-Charles Marié; Carol A Mulrooney; Giovanni Muncipinto; Morgan Welzel-O'Shea; Laura M Panko; Ann Rowley; Byung-Chul Suh; Meryl Thomas; Florence F Wagner; Jingqiang Wei; Michael A Foley; Lisa A Marcaurelle
Journal:  J Org Chem       Date:  2012-08-10       Impact factor: 4.354

4.  Spread of artemisinin resistance in Plasmodium falciparum malaria.

Authors:  Elizabeth A Ashley; Mehul Dhorda; Rick M Fairhurst; Chanaki Amaratunga; Parath Lim; Seila Suon; Sokunthea Sreng; Jennifer M Anderson; Sivanna Mao; Baramey Sam; Chantha Sopha; Char Meng Chuor; Chea Nguon; Siv Sovannaroth; Sasithon Pukrittayakamee; Podjanee Jittamala; Kesinee Chotivanich; Kitipumi Chutasmit; Chaiyaporn Suchatsoonthorn; Ratchadaporn Runcharoen; Tran Tinh Hien; Nguyen Thanh Thuy-Nhien; Ngo Viet Thanh; Nguyen Hoan Phu; Ye Htut; Kay-Thwe Han; Kyin Hla Aye; Olugbenga A Mokuolu; Rasaq R Olaosebikan; Olaleke O Folaranmi; Mayfong Mayxay; Maniphone Khanthavong; Bouasy Hongvanthong; Paul N Newton; Marie A Onyamboko; Caterina I Fanello; Antoinette K Tshefu; Neelima Mishra; Neena Valecha; Aung Pyae Phyo; Francois Nosten; Poravuth Yi; Rupam Tripura; Steffen Borrmann; Mahfudh Bashraheil; Judy Peshu; M Abul Faiz; Aniruddha Ghose; M Amir Hossain; Rasheda Samad; M Ridwanur Rahman; M Mahtabuddin Hasan; Akhterul Islam; Olivo Miotto; Roberto Amato; Bronwyn MacInnis; Jim Stalker; Dominic P Kwiatkowski; Zbynek Bozdech; Atthanee Jeeyapant; Phaik Yeong Cheah; Tharisara Sakulthaew; Jeremy Chalk; Benjamas Intharabut; Kamolrat Silamut; Sue J Lee; Benchawan Vihokhern; Chanon Kunasol; Mallika Imwong; Joel Tarning; Walter J Taylor; Shunmay Yeung; Charles J Woodrow; Jennifer A Flegg; Debashish Das; Jeffery Smith; Meera Venkatesan; Christopher V Plowe; Kasia Stepniewska; Philippe J Guerin; Arjen M Dondorp; Nicholas P Day; Nicholas J White
Journal:  N Engl J Med       Date:  2014-07-31       Impact factor: 91.245

5.  A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.

Authors:  Margaret A Phillips; Julie Lotharius; Kennan Marsh; John White; Anthony Dayan; Karen L White; Jacqueline W Njoroge; Farah El Mazouni; Yanbin Lao; Sreekanth Kokkonda; Diana R Tomchick; Xiaoyi Deng; Trevor Laird; Sangeeta N Bhatia; Sandra March; Caroline L Ng; David A Fidock; Sergio Wittlin; Maria Lafuente-Monasterio; Francisco Javier Gamo Benito; Laura Maria Sanz Alonso; Maria Santos Martinez; Maria Belen Jimenez-Diaz; Santiago Ferrer Bazaga; Iñigo Angulo-Barturen; John N Haselden; James Louttit; Yi Cui; Arun Sridhar; Anna-Marie Zeeman; Clemens Kocken; Robert Sauerwein; Koen Dechering; Vicky M Avery; Sandra Duffy; Michael Delves; Robert Sinden; Andrea Ruecker; Kristina S Wickham; Rosemary Rochford; Janet Gahagen; Lalitha Iyer; Ed Riccio; Jon Mirsalis; Ian Bathhurst; Thomas Rueckle; Xavier Ding; Brice Campo; Didier Leroy; M John Rogers; Pradipsinh K Rathod; Jeremy N Burrows; Susan A Charman
Journal:  Sci Transl Med       Date:  2015-07-15       Impact factor: 17.956

6.  Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment.

Authors:  Rithea Leang; Walter R J Taylor; Denis Mey Bouth; Lijiang Song; Joel Tarning; Meng Chuor Char; Saorin Kim; Benoit Witkowski; Valentine Duru; Anais Domergue; Nimol Khim; Pascal Ringwald; Didier Menard
Journal:  Antimicrob Agents Chemother       Date:  2015-05-26       Impact factor: 5.191

7.  A broad analysis of resistance development in the malaria parasite.

Authors:  Victoria C Corey; Amanda K Lukens; Eva S Istvan; Marcus C S Lee; Virginia Franco; Pamela Magistrado; Olivia Coburn-Flynn; Tomoyo Sakata-Kato; Olivia Fuchs; Nina F Gnädig; Greg Goldgof; Maria Linares; Maria G Gomez-Lorenzo; Cristina De Cózar; Maria Jose Lafuente-Monasterio; Sara Prats; Stephan Meister; Olga Tanaseichuk; Melanie Wree; Yingyao Zhou; Paul A Willis; Francisco-Javier Gamo; Daniel E Goldberg; David A Fidock; Dyann F Wirth; Elizabeth A Winzeler
Journal:  Nat Commun       Date:  2016-06-15       Impact factor: 14.919

Review 8.  Aminoacyl-tRNA synthetases as drug targets in eukaryotic parasites.

Authors:  James S Pham; Karen L Dawson; Katherine E Jackson; Erin E Lim; Charisse Flerida A Pasaje; Kelsey E C Turner; Stuart A Ralph
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2013-11-11       Impact factor: 4.077

9.  A novel multiple-stage antimalarial agent that inhibits protein synthesis.

Authors:  Beatriz Baragaña; Irene Hallyburton; Marcus C S Lee; Neil R Norcross; Raffaella Grimaldi; Thomas D Otto; William R Proto; Andrew M Blagborough; Stephan Meister; Grennady Wirjanata; Andrea Ruecker; Leanna M Upton; Tara S Abraham; Mariana J Almeida; Anupam Pradhan; Achim Porzelle; María Santos Martínez; Torsten Luksch; Judith M Bolscher; Andrew Woodland; Suzanne Norval; Fabio Zuccotto; John Thomas; Frederick Simeons; Laste Stojanovski; Maria Osuna-Cabello; Paddy M Brock; Tom S Churcher; Katarzyna A Sala; Sara E Zakutansky; María Belén Jiménez-Díaz; Laura Maria Sanz; Jennifer Riley; Rajshekhar Basak; Michael Campbell; Vicky M Avery; Robert W Sauerwein; Koen J Dechering; Rintis Noviyanti; Brice Campo; Julie A Frearson; Iñigo Angulo-Barturen; Santiago Ferrer-Bazaga; Francisco Javier Gamo; Paul G Wyatt; Didier Leroy; Peter Siegl; Michael J Delves; Dennis E Kyle; Sergio Wittlin; Jutta Marfurt; Ric N Price; Robert E Sinden; Elizabeth A Winzeler; Susan A Charman; Lidiya Bebrevska; David W Gray; Simon Campbell; Alan H Fairlamb; Paul A Willis; Julian C Rayner; David A Fidock; Kevin D Read; Ian H Gilbert
Journal:  Nature       Date:  2015-06-18       Impact factor: 49.962
  9 in total
  1 in total

1.  Antimalarial activity of Malaria Box Compounds against Plasmodium falciparum clinical isolates.

Authors:  Jersley D Chirawurah; Felix Ansah; Prince B Nyarko; Samuel Duodu; Yaw Aniweh; Gordon A Awandare
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2017-10-16       Impact factor: 4.077
  1 in total

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