Literature DB >> 27731334

Julian Davies and the discovery of kanamycin resistance transposon Tn5.

Douglas E Berg1.   

Abstract

This paper recounts some of my fond memories of a collaboration between Julian Davies and myself that started in 1974 in Geneva and that led to our serendipitous discovery of the bacterial kanamycin resistance transposon Tn5, and aspects of the lasting positive impact of our interaction and discovery on me and the community. Tn5 was one of the first antibiotic resistance transposons to be found. Its analysis over the ensuing decades provided valuable insights into mechanisms and control of transposition, and led to its use as a much-valued tool in diverse areas of molecular genetics, as also will be discussed here.

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Year:  2016        PMID: 27731334     DOI: 10.1038/ja.2016.120

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  78 in total

1.  The significance of responses of the genome to challenge.

Authors:  B McClintock
Journal:  Science       Date:  1984-11-16       Impact factor: 47.728

Review 2.  Quorum sensing: cell-to-cell communication in bacteria.

Authors:  Christopher M Waters; Bonnie L Bassler
Journal:  Annu Rev Cell Dev Biol       Date:  2005       Impact factor: 13.827

Review 3.  Specialized microbial metabolites: functions and origins.

Authors:  Julian Davies
Journal:  J Antibiot (Tokyo)       Date:  2013-06-12       Impact factor: 2.649

4.  A new enzyme in Escherichia coli carrying R-factor phosphorylating 3'-hydroxyl of butirosin A, kanamycin, neamine and ribostamycin.

Authors:  M Yagisawa; H Yamamoto; H Naganawa; S Kondo; T Takeuchi
Journal:  J Antibiot (Tokyo)       Date:  1972-12       Impact factor: 2.649

5.  Restriction enzyme cleavage map of Tn10, a transposon which encodes tetracycline resistance.

Authors:  R A Jorgensen; D E Berg; B Allet; W S Reznikoff
Journal:  J Bacteriol       Date:  1979-01       Impact factor: 3.490

6.  Emergence of tetracycline resistance in Helicobacter pylori: multiple mutational changes in 16S ribosomal DNA and other genetic loci.

Authors:  Daiva Dailidiene; M Teresita Bertoli; Jolanta Miciuleviciene; Asish K Mukhopadhyay; Giedrius Dailide; Mario Alberto Pascasio; Limas Kupcinskas; Douglas E Berg
Journal:  Antimicrob Agents Chemother       Date:  2002-12       Impact factor: 5.191

Review 7.  The chemical biology of protein phosphorylation.

Authors:  Mary Katherine Tarrant; Philip A Cole
Journal:  Annu Rev Biochem       Date:  2009       Impact factor: 23.643

8.  Genome construction between bacterial species in vitro: replication and expression of Staphylococcus plasmid genes in Escherichia coli.

Authors:  A C Chang; S N Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

Review 9.  Bacterial small-molecule signaling pathways.

Authors:  Andrew Camilli; Bonnie L Bassler
Journal:  Science       Date:  2006-02-24       Impact factor: 47.728

10.  Grete Kellenberger-Gujer: Molecular biology research pioneer.

Authors:  Sandra Citi; Douglas E Berg
Journal:  Bacteriophage       Date:  2016-04-05
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