Literature DB >> 27730542

MicroRNAs as biomarkers in the diagnosis and treatment of chondrosarcoma.

Feifei Pu1, Fengxia Chen2, Zengwu Shao3.   

Abstract

MicroRNAs are a group of small non-coding RNAs that play a complex role in post-transcriptional gene expression and can be used for diagnosis, prognosis, and targeted treatment. Despite advances in diagnosis and treatment of chondrosarcoma, its underpinning molecular mechanisms still remain elusive. Given the recent increasing knowledge base of micro RNA (miRNA) roles in neoplasia, both as oncogenes and tumor suppressor genes, this review will focus on discussing the available data on expression profiles and potential roles of miRNA in chondrosarcoma. Accumulating evidence suggests that microRNAs have the potential to be used in the future for clinical management of chondrosarcoma.

Entities:  

Keywords:  Chondrosarcoma; Diagnosis; Prognosis; Therapy; miRNA; microRNA

Year:  2016        PMID: 27730542     DOI: 10.1007/s13277-016-5468-1

Source DB:  PubMed          Journal:  Tumour Biol        ISSN: 1010-4283


  33 in total

1.  Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells.

Authors:  Wenna Liang; Xihai Li; Yachan Li; Candong Li; Bizheng Gao; Huijuan Gan; Sumin Li; Jianying Shen; Jie Kang; Shanshan Ding; Xuejuan Lin; Linghong Liao
Journal:  Int J Oncol       Date:  2013-10-30       Impact factor: 5.650

Review 2.  Novel agents and associated toxicities of inhibitors of the pi3k/Akt/mtor pathway for the treatment of breast cancer.

Authors:  S Chia; S Gandhi; A A Joy; S Edwards; M Gorr; S Hopkins; J Kondejewski; J P Ayoub; N Califaretti; D Rayson; S F Dent
Journal:  Curr Oncol       Date:  2015-02       Impact factor: 3.677

Review 3.  AMPK--sensing energy while talking to other signaling pathways.

Authors:  D Grahame Hardie
Journal:  Cell Metab       Date:  2014-10-30       Impact factor: 27.287

Review 4.  Dissecting the Dual Role of AMPK in Cancer: From Experimental to Human Studies.

Authors:  Giorgia Zadra; Julie L Batista; Massimo Loda
Journal:  Mol Cancer Res       Date:  2015-05-08       Impact factor: 5.852

5.  The expression of miR-181a-5p and miR-371b-5p in chondrosarcoma.

Authors:  S Mutlu; H Mutlu; S Kirkbes; S Eroglu; Y S Kabukcuoglu; F Kabukcuoglu; T M Duymus; M ISık; M Ulasli
Journal:  Eur Rev Med Pharmacol Sci       Date:  2015-07       Impact factor: 3.507

6.  Analysis of microRNAs expressions in chondrosarcoma.

Authors:  Teruhito Yoshitaka; Akira Kawai; Shigeru Miyaki; Kunihiko Numoto; Kazutaka Kikuta; Toshifumi Ozaki; Martin Lotz; Hiroshi Asahara
Journal:  J Orthop Res       Date:  2013-08-12       Impact factor: 3.494

7.  Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1.

Authors:  Karina Galoian; Amir Qureshi; Gianluca D'Ippolito; Paul C Schiller; Marco Molinari; Andrea L Johnstone; Shaun P Brothers; Ana C Paz; H T Temple
Journal:  Int J Oncol       Date:  2015-06-18       Impact factor: 5.650

8.  MicroRNA-494 inhibits cell proliferation and invasion of chondrosarcoma cells in vivo and in vitro by directly targeting SOX9.

Authors:  Jingyuan Li; Lijuan Wang; Zongzhi Liu; Chao Zu; Fanfan Xing; Pei Yang; Yongkang Yang; Xiaoqian Dang; Kunzheng Wang
Journal:  Oncotarget       Date:  2015-09-22

9.  The expression of the PI3K/AKT/mTOR pathway in gastric cancer and its role in gastric cancer prognosis.

Authors:  Jieer Ying; Qi Xu; Bixia Liu; Gu Zhang; Lei Chen; Hongming Pan
Journal:  Onco Targets Ther       Date:  2015-09-01       Impact factor: 4.147

Review 10.  MicroRNAs transported by exosomes in body fluids as mediators of intercellular communication in cancer.

Authors:  Iván Salido-Guadarrama; Sandra Romero-Cordoba; Oscar Peralta-Zaragoza; Alfredo Hidalgo-Miranda; Mauricio Rodríguez-Dorantes
Journal:  Onco Targets Ther       Date:  2014-07-21       Impact factor: 4.147

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  4 in total

Review 1.  The role of microRNAs in the osteogenic and chondrogenic differentiation of mesenchymal stem cells and bone pathologies.

Authors:  Maria Rosa Iaquinta; Carmen Lanzillotti; Chiara Mazziotta; Ilaria Bononi; Francesca Frontini; Elisa Mazzoni; Lucia Oton-Gonzalez; John Charles Rotondo; Elena Torreggiani; Mauro Tognon; Fernanda Martini
Journal:  Theranostics       Date:  2021-04-30       Impact factor: 11.556

Review 2.  The Roles of Noncoding RNAs in the Development of Osteosarcoma Stem Cells and Potential Therapeutic Targets.

Authors:  Jinxin Liu; Guanning Shang
Journal:  Front Cell Dev Biol       Date:  2022-02-16

3.  Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids.

Authors:  Clément Veys; Abderrahim Benmoussa; Romain Contentin; Amandine Duchemin; Emilie Brotin; Jérôme E Lafont; Yannick Saintigny; Laurent Poulain; Christophe Denoyelle; Magali Demoor; Florence Legendre; Philippe Galéra
Journal:  Int J Mol Sci       Date:  2021-05-25       Impact factor: 5.923

4.  Long noncoding RNA DANCR regulates miR-1305-Smad 4 axis to promote chondrogenic differentiation of human synovium-derived mesenchymal stem cells.

Authors:  Lei Zhang; Xiangyi Sun; Shuo Chen; Chao Yang; Ben Shi; Liwu Zhou; Jianning Zhao
Journal:  Biosci Rep       Date:  2017-07-21       Impact factor: 3.840

  4 in total

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