Literature DB >> 27728798

Senescence and Cancer: In the Name of Immunosuppression.

Susana Llanos1, Manuel Serrano2.   

Abstract

Senescent cells and cancer cells recruit immunosuppressive myeloid cells. In this issue of Cancer Cell, Eggert et al. report that senescent cells recruit immature myeloid cells (iMCs) through the secretion of the CCL2 cytokine and that these iMCs have pro- or anti-tumorigenic activities, depending on the cellular context.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27728798     DOI: 10.1016/j.ccell.2016.09.015

Source DB:  PubMed          Journal:  Cancer Cell        ISSN: 1535-6108            Impact factor:   31.743


  6 in total

Review 1.  A role for cellular senescence in birth timing.

Authors:  Jeeyeon M Cha; David M Aronoff
Journal:  Cell Cycle       Date:  2017-09-25       Impact factor: 4.534

2.  Anti-Tumorigenic Effect of a Novel Derivative of 2-Hydroxyoleic Acid and the Endocannabinoid Anandamide on Neuroblastoma Cells.

Authors:  Hana Golan; Raphael Mechoulam; Reem Smoum; Efrat Cohen-Zada; Sara Pri-Chen; Sapir Wiener; Igor Grinberg; Dekel D Bar-Lev; Christeeneh G Haj; Tamar Fisher; Amos Toren
Journal:  Biomedicines       Date:  2022-06-29

3.  Polysaccharides Derived from Saposhnikovia divaricata May Suppress Breast Cancer Through Activating Macrophages.

Authors:  Jingxian Ding; Yonghong Guo; Xiaoliu Jiang; Qingge Li; Kai Li; Min Liu; Wenbing Fu; Yali Cao
Journal:  Onco Targets Ther       Date:  2020-10-22       Impact factor: 4.147

Review 4.  Senescence in the Development and Response to Cancer with Immunotherapy: A Double-Edged Sword.

Authors:  Anthony M Battram; Mireia Bachiller; Beatriz Martín-Antonio
Journal:  Int J Mol Sci       Date:  2020-06-18       Impact factor: 5.923

Review 5.  Molecular Mechanisms of Senescence and Implications for the Treatment of Myeloid Malignancies.

Authors:  Philipp Ernst; Florian H Heidel
Journal:  Cancers (Basel)       Date:  2021-02-04       Impact factor: 6.639

6.  Chemotherapy-induced cellular senescence suppresses progression of Notch-driven T-ALL.

Authors:  Ying Zhang; Justin Gundelach; Lonnie D Lindquist; Darren J Baker; Jan van Deursen; Richard J Bram
Journal:  PLoS One       Date:  2019-10-29       Impact factor: 3.240

  6 in total

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