| Literature DB >> 27728782 |
Florian Hoss1, Christina F Budden1, Eicke Latz2.
Abstract
When bacteria infect a cell, the bacterial membrane partially shields microbial structures from the immune system, preventing detection and clearance. In a recent issue of Cell, Man et al. (2016) show that the interferon-inducible protein IRGB10 liberates bacterial ligands for sensing by both the AIM2 and the non-canonical NLRP3 inflammasomes.Entities:
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Year: 2016 PMID： 27728782 DOI： 10.1016/j.devcel.2016.09.026
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270