Literature DB >> 27726268

A survey of youth with new onset type 1 diabetes: Opportunities to reduce diabetic ketoacidosis.

Luke Baldelli1, Ben Flitter1, Laura Pyle2,3, David M Maahs2,4, Georgeanna Klingensmith2,4, Robert Slover2,4, G Todd Alonso2,4.   

Abstract

OBJECTIVE: Pediatric patients in Colorado with new onset type 1 diabetes (T1D) presenting with diabetic ketoacidosis (DKA) increased from 29.9% to 46.2% from 1998 to 2012. The purpose of this study was to compare differences between patients with newly diagnosed T1D who presented in DKA with those who did not across three domains: sociodemographic factors, access to medical care, and medical provider factors, aiming to identify potential targets for intervention.
METHODS: Sixty-one patients <17 years of age with T1D duration <6 months completed the questionnaire. Groups were compared using Fisher's exact test or the Kruskal-Wallis test.
RESULTS: Parents of 28% of patients researched their child's symptoms on the Internet prior to diagnosis. At the first healthcare visit for symptoms of T1D, 23% were not diagnosed. There were no significant differences between groups (DKA vs non-DKA) in demographics, first healthcare setting for T1D symptoms, provider type at first visit or at diagnosis, insurance status, or specific barriers to care. DKA patients had a longer interval between previous well visit to diagnosis (median 172 vs 263 days, P = 0.01). Non-DKA patients were more likely to have blood glucose measured at P = 0.02, and had fewer symptoms prior to (P = 0.01) the first visit for diabetes symptoms. Parents of non-DKA patients were more likely to be familiar with symptoms of diabetes (P < 0.001) and to suspect diabetes (P = 0.01).
CONCLUSION: Targets for campaigns to prevent DKA include increasing provider glucose and ketone testing, increasing public knowledge about diabetes, and understanding how socio-demographic factors may delay T1D diagnosis.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  diabetic ketoacidosis; new onset diabetes; pediatrics; primary care; type 1

Mesh:

Substances:

Year:  2016        PMID: 27726268      PMCID: PMC5388598          DOI: 10.1111/pedi.12455

Source DB:  PubMed          Journal:  Pediatr Diabetes        ISSN: 1399-543X            Impact factor:   4.866


  18 in total

1.  Campaign for diabetic ketoacidosis prevention still effective 8 years later.

Authors:  Maurizio Vanelli; Giovanni Chiari; Silvia Lacava; Brunella Iovane
Journal:  Diabetes Care       Date:  2007-04       Impact factor: 19.112

2.  Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support.

Authors:  Paul A Harris; Robert Taylor; Robert Thielke; Jonathon Payne; Nathaniel Gonzalez; Jose G Conde
Journal:  J Biomed Inform       Date:  2008-09-30       Impact factor: 6.317

3.  Incidence of diabetic ketoacidosis at diagnosis of type 1 diabetes in Colorado youth, 1998-2012.

Authors:  Arleta Rewers; Fran Dong; Robert H Slover; Georgeanna J Klingensmith; Marian Rewers
Journal:  JAMA       Date:  2015-04-21       Impact factor: 56.272

4.  Fluid management in pediatric patients with DKA and rates of suspected clinical cerebral edema.

Authors:  Daniel S Hsia; Sarah G Tarai; Amir Alimi; Jorge A Coss-Bu; Morey W Haymond
Journal:  Pediatr Diabetes       Date:  2015-03-19       Impact factor: 4.866

5.  Identifying targets to reduce the incidence of diabetic ketoacidosis at diagnosis of type 1 diabetes in the UK.

Authors:  K Lokulo-Sodipe; R J Moon; J A Edge; J H Davies
Journal:  Arch Dis Child       Date:  2014-01-06       Impact factor: 3.791

Review 6.  Hyperglycemic crises in adult patients with diabetes: a consensus statement from the American Diabetes Association.

Authors:  Abbas E Kitabchi; Guillermo E Umpierrez; Mary Beth Murphy; Robert A Kreisberg
Journal:  Diabetes Care       Date:  2006-12       Impact factor: 19.112

Review 7.  Morbidity and mortality of diabetic ketoacidosis with and without insulin pump care.

Authors:  Jaime Realsen; Hannah Goettle; H Peter Chase
Journal:  Diabetes Technol Ther       Date:  2012-09-25       Impact factor: 6.118

8.  Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up.

Authors:  Helena Elding Larsson; Kendra Vehik; Ronny Bell; Dana Dabelea; Lawrence Dolan; Catherine Pihoker; Mikael Knip; Riitta Veijola; Bengt Lindblad; Ulf Samuelsson; Reinhard Holl; Michael J Haller
Journal:  Diabetes Care       Date:  2011-10-04       Impact factor: 17.152

9.  The pathway to diagnosis of type 1 diabetes in children: a questionnaire study.

Authors:  Juliet A Usher-Smith; Matthew J Thompson; Hannah Zhu; Stephen J Sharp; Fiona M Walter
Journal:  BMJ Open       Date:  2015-03-17       Impact factor: 2.692

10.  'Looking for the needle in the haystack': a qualitative study of the pathway to diagnosis of type 1 diabetes in children.

Authors:  Juliet A Usher-Smith; Matthew J Thompson; Fiona M Walter
Journal:  BMJ Open       Date:  2013-12-03       Impact factor: 2.692

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  11 in total

1.  Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Colorado Children, 2010-2017.

Authors:  G Todd Alonso; Alex Coakley; Laura Pyle; Katherine Manseau; Sarah Thomas; Arleta Rewers
Journal:  Diabetes Care       Date:  2019-10-10       Impact factor: 19.112

Review 2.  Psychosocial Needs for Newly Diagnosed Youth with Type 1 Diabetes and Their Families.

Authors:  Susana R Patton; David Maahs; Priya Prahalad; Mark A Clements
Journal:  Curr Diab Rep       Date:  2022-06-21       Impact factor: 5.430

3.  Diabetic ketoacidosis: knowledge and practice among patients with diabetes attending three specialized diabetes clinics in Khartoum, Sudan.

Authors:  Almutasim Billah Elbagir Elhassan; Marwa Mohammed Elrasheed Saad; Mohammed Suliman Tawer Salman; Abazr Ibrahim; Almigdad Ali; Asmaa Abd Elaal Abd Alla; Fadwa Mohammed Saad
Journal:  Pan Afr Med J       Date:  2022-04-13

4.  Misdiagnosis and Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes: Patient and Caregiver Perspectives.

Authors:  Cynthia Muñoz; Anna Floreen; Colleen Garey; Tom Karlya; David Jelley; G Todd Alonso; Alicia McAuliffe-Fogarty
Journal:  Clin Diabetes       Date:  2019-07

5.  Risk of ketoacidosis in children at the time of diabetes mellitus diagnosis by primary caregiver status: a population-based retrospective cohort study.

Authors:  Meranda Nakhla; Elham Rahme; Marc Simard; Isabelle Larocque; Laurent Legault; Patricia Li
Journal:  CMAJ       Date:  2018-04-09       Impact factor: 8.262

6.  Cost and healthcare utilization analysis of culturally sensitive, shared medical appointment model for Latino children with type 1 diabetes.

Authors:  Heather T Gold; Elizabeth Pirraglia; Elbert S Huang; Wen Wan; Andrea B Pascual; Ryan James Jensen; Andrea Gerard Gonzalez
Journal:  Pediatr Diabetes       Date:  2021-05-06       Impact factor: 4.866

7.  Parent and Pediatrician Preferences for Type 1 Diabetes Screening in the U.S.

Authors:  Jessica L Dunne; Anne Koralova; Jessie Sutphin; Jesse S Bushman; Barbara Fontanals-Ciera; Joshua R Coulter; Campbell T Hutton; Marian J Rewers; Carol Mansfield
Journal:  Diabetes Care       Date:  2020-12-10       Impact factor: 19.112

8.  "Puddles on the Road": Hurdles in the Pathway from Symptoms to Diagnosis and Treatment in Children with Type 1 Diabetes.

Authors:  Latika Rohilla; Rakesh Kumar; Priyanka Walia; Jaivinder Yadav; Devi Dayal
Journal:  Indian J Endocrinol Metab       Date:  2021-07-21

9.  Alarming Increase of Ketoacidosis Prevalence at Type 1 Diabetes-Onset in Austria-Results From a Nationwide Registry.

Authors:  Katrin Nagl; Thomas Waldhör; Sabine E Hofer; Maria Fritsch; Dagmar Meraner; Christine Prchla; Birgit Rami-Merhar; Elke Fröhlich-Reiterer
Journal:  Front Pediatr       Date:  2022-02-14       Impact factor: 3.418

10.  Socioeconomic Inequalities Increase the Probability of Ketoacidosis at Diagnosis of Type 1 Diabetes: A 2014-2016 Nationwide Study of 2,679 Italian Children.

Authors:  Rosaria Gesuita; Claudio Maffeis; Riccardo Bonfanti; Francesca Cardella; Felice Citriniti; Giuseppe D'Annunzio; Adriana Franzese; Dario Iafusco; Antonio Iannilli; Fortunato Lombardo; Giulio Maltoni; Ippolita Patrizia Patera; Elvira Piccinno; Barbara Predieri; Ivana Rabbone; Carlo Ripoli; Sonia Toni; Riccardo Schiaffini; Renee Bowers; Valentino Cherubini
Journal:  Front Pediatr       Date:  2020-10-22       Impact factor: 3.418

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