Literature DB >> 277253

A preliminary clinical study in the use of misonidazole in cancer of the head and neck.

R Sealy.   

Abstract

The value of misonidazole in advanced head and neck cancer was examined in 3 ways and the preliminary results are reported in a randomized study with large fractions of irradiation, when misonidazole appeared to confer no advantage; whereas in previously (partially) treated patients misonidazole was possibly useful. The combination of hyperbaric oxygen and misonidazole did not appear to be toxic.

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Year:  1978        PMID： 277253      PMCID： PMC2149372     

Source DB:  PubMed          Journal:  Br J Cancer Suppl        ISSN： 0306-9443


  4 in total

Review 1.  Hyperbaric oxygenation for tumour sensitisation to radiotherapy.

Authors:  Michael H Bennett; John Feldmeier; Robert Smee; Christopher Milross
Journal:  Cochrane Database Syst Rev       Date:  2012-04-18

Review 2.  Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy.

Authors:  Ambika Parmar; Michaelina Macluskey; Niall Mc Goldrick; David I Conway; Anne-Marie Glenny; Janet E Clarkson; Helen V Worthington; Kelvin Kw Chan
Journal:  Cochrane Database Syst Rev       Date:  2021-12-20

Review 3.  Hyperbaric oxygenation for tumour sensitisation to radiotherapy.

Authors:  Michael H Bennett; John Feldmeier; Robert Smee; Christopher Milross
Journal:  Cochrane Database Syst Rev       Date:  2018-04-11

4.  A phase I study of misonidazole and pelvic irradiation in patients with carcinoma of cervix.

Authors:  G M Thomas; A M Rauth; B E Black; B J Cummings; V L Sorenti; R S Bush
Journal:  Br J Cancer       Date:  1982-06       Impact factor: 7.640
  4 in total

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