| Literature DB >> 27725108 |
M Alba Mañé-Martínez1, Bob Olsson2, Laura Bau3, Elisabet Matas3, Álvaro Cobo-Calvo3, Ulf Andreasson2, Kaj Blennow2, Lucia Romero-Pinel3, Sergio Martínez-Yélamos3, Henrik Zetterberg4.
Abstract
In the present study, CSF concentrations of NFL, t-tau, p-tau, GFAP, S-100B, YKL-40, MCP-1, α-sAPP, β-sAPP, and Aβ38, Aβ40, Aβ42 were measured in 324 MS patients to test whether a correlation among the biomarkers exists and whether the profile of CSF biomarkers varies among the different types of MS. The CSF concentrations of NFL were significantly higher in RRMS while CSF concentrations of GFAP were higher in PPMS. CSF concentrations of NFL correlated with YKL-40 in CIS patients while CSF concentrations of GFAP correlated with YKL-40 in RRMS patients.Entities:
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Year: 2016 PMID： 27725108 DOI： 10.1016/j.jneuroim.2016.08.004
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478