Literature DB >> 27723718

Progress towards generation of human haematopoietic stem cells.

Lara Wahlster1,2, George Q Daley1.   

Abstract

De novo generation of haematopoietic stem cells from different human pluripotent stem cell sources remains a high priority for haematology and regenerative medicine. At present, efficient derivation of functional haematopoietic stem cells with the capability for definitive in vivo engraftment and multi-lineage potential remains challenging. Here, we discuss recent progress and strategies to overcome obstacles that have thwarted past efforts. In addition, we review promising advances in the generation of mature blood lineages and the potential of induced pluripotent stem cells.

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Year:  2016        PMID： 27723718     DOI： 10.1038/ncb3419

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  87 in total

1.  MiR-142-3p controls the specification of definitive hemangioblasts during ontogeny.

Authors:  Rachael Nimmo; Aldo Ciau-Uitz; Cristina Ruiz-Herguido; Shamit Soneji; Anna Bigas; Roger Patient; Tariq Enver
Journal:  Dev Cell       Date:  2013-08-01       Impact factor: 12.270

2.  Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells.

Authors:  Kyung-Dal Choi; Maxim Vodyanik; Igor I Slukvin
Journal:  Nat Protoc       Date:  2011-02-17       Impact factor: 13.491

Review 3.  Long noncoding RNAs during normal and malignant hematopoiesis.

Authors:  Juan R Alvarez-Dominguez; Wenqian Hu; Austin A Gromatzky; Harvey F Lodish
Journal:  Int J Hematol       Date:  2014-03-09       Impact factor: 2.490

4.  Reprogramming of human somatic cells to pluripotency with defined factors.

Authors:  In-Hyun Park; Rui Zhao; Jason A West; Akiko Yabuuchi; Hongguang Huo; Tan A Ince; Paul H Lerou; M William Lensch; George Q Daley
Journal:  Nature       Date:  2007-12-23       Impact factor: 49.962

5.  Conversion of human fibroblasts into monocyte-like progenitor cells.

Authors:  Julian Pulecio; Emmanuel Nivet; Ignacio Sancho-Martinez; Marianna Vitaloni; Guillermo Guenechea; Yun Xia; Leo Kurian; Ilir Dubova; Juan Bueren; Leopoldo Laricchia-Robbio; Juan Carlos Izpisua Belmonte
Journal:  Stem Cells       Date:  2014-11       Impact factor: 6.277

6.  Hematopoietic stem cell development is dependent on blood flow.

Authors:  Trista E North; Wolfram Goessling; Marian Peeters; Pulin Li; Craig Ceol; Allegra M Lord; Gerhard J Weber; James Harris; Claire C Cutting; Paul Huang; Elaine Dzierzak; Leonard I Zon
Journal:  Cell       Date:  2009-05-15       Impact factor: 41.582

7.  Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.

Authors:  Peter Geon Kim; Haruko Nakano; Partha P Das; Michael J Chen; R Grant Rowe; Stephanie S Chou; Samantha J Ross; Kathleen M Sakamoto; Leonard I Zon; Thorsten M Schlaeger; Stuart H Orkin; Atsushi Nakano; George Q Daley
Journal:  J Exp Med       Date:  2015-04-13       Impact factor: 14.307

8.  CellNet: network biology applied to stem cell engineering.

Authors:  Patrick Cahan; Hu Li; Samantha A Morris; Edroaldo Lummertz da Rocha; George Q Daley; James J Collins
Journal:  Cell       Date:  2014-08-14       Impact factor: 41.582

9.  Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells.

Authors:  Christopher M Sturgeon; Andrea Ditadi; Geneve Awong; Marion Kennedy; Gordon Keller
Journal:  Nat Biotechnol       Date:  2014-05-18       Impact factor: 54.908

10.  A Quantitative Proteomic Analysis of Hemogenic Endothelium Reveals Differential Regulation of Hematopoiesis by SOX17.

Authors:  Raedun L Clarke; Aaron M Robitaille; Randall T Moon; Gordon Keller
Journal:  Stem Cell Reports       Date:  2015-08-11       Impact factor: 7.765
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  33 in total

Review 1.  Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes.

Authors:  Eliver Ghosn; Momoko Yoshimoto; Hiromitsu Nakauchi; Irving L Weissman; Leonore A Herzenberg
Journal:  Development       Date:  2019-08-01       Impact factor: 6.868

2.  Emergence of CD43-Expressing Hematopoietic Progenitors from Human Induced Pluripotent Stem Cells.

Authors:  Katharina U Kessel; Anika Bluemke; Hans R Schöler; Holm Zaehres; Peter Schlenke; Isabel Dorn
Journal:  Transfus Med Hemother       Date:  2017-05-29       Impact factor: 3.747

3.  MLL-AF4, a double-edged sword for iPSC respecification into HSPCs.

Authors:  Bernd B Zeisig; Chi Wai Eric So
Journal:  Proc Natl Acad Sci U S A       Date:  2018-02-14       Impact factor: 11.205

Review 4.  Modeling Leukemia with Human Induced Pluripotent Stem Cells.

Authors:  Eirini P Papapetrou
Journal:  Cold Spring Harb Perspect Med       Date:  2019-12-02       Impact factor: 6.915

5.  Mechanoregulation in hematopoiesis and hematologic disorders.

Authors:  Paulina D Horton; Sandeep Dumbali; Pamela L Wenzel
Journal:  Curr Stem Cell Rep       Date:  2020-05-21

6.  Conversion of adult endothelium to immunocompetent haematopoietic stem cells.

Authors:  Raphael Lis; Charles C Karrasch; Michael G Poulos; Balvir Kunar; David Redmond; Jose G Barcia Duran; Chaitanya R Badwe; William Schachterle; Michael Ginsberg; Jenny Xiang; Arash Rafii Tabrizi; Koji Shido; Zev Rosenwaks; Olivier Elemento; Nancy A Speck; Jason M Butler; Joseph M Scandura; Shahin Rafii
Journal:  Nature       Date:  2017-05-17       Impact factor: 49.962

Review 7.  Recapitulating kidney development: Progress and challenges.

Authors:  Melissa H Little; Santhosh V Kumar; Thomas Forbes
Journal:  Semin Cell Dev Biol       Date:  2018-09-20       Impact factor: 7.727

Review 8.  Induced pluripotent stem cells in disease modelling and drug discovery.

Authors:  R Grant Rowe; George Q Daley
Journal:  Nat Rev Genet       Date:  2019-07       Impact factor: 53.242

Review 9.  The hemogenic endothelium: a critical source for the generation of PSC-derived hematopoietic stem and progenitor cells.

Authors:  Lucas Lange; Michael Morgan; Axel Schambach
Journal:  Cell Mol Life Sci       Date:  2021-02-09       Impact factor: 9.261

10.  Studying leukemia stem cell properties and vulnerabilities with human iPSCs.

Authors:  Nikolaos Spyrou; Eirini P Papapetrou
Journal:  Stem Cell Res       Date:  2020-12-10       Impact factor: 1.587
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