Hye-Kyung Park1,2,3, Kai-Chung Cheng2, Afua O Tetteh1,4, Lynn M Hildemann2, Kari C Nadeau1,4. 1. a Division of Pulmonary and Critical Care, Department of Medicine, Stanford University School of Medicine , Stanford , CA , USA. 2. b Civil and Environmental Engineering Department , Stanford University , Stanford , CA , USA. 3. c Department of Internal Medicine , Pusan National University School of Medicine , Busan , Korea. 4. d Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine , Stanford , CA , USA.
Abstract
OBJECTIVE: Epidemiologic studies indicate that indoor air pollution is correlated with morbidity caused by allergic diseases. We evaluated the effectiveness of reducing the levels of indoor fine particulate matter <2.5 micrometer diameter (PM2.5) in Fresno, California using air purifiers on health outcomes in children with asthma and/or allergic rhinitis. METHODS: The active group (with air purifiers) and the control group consisted of eight houses each. Air purifiers were installed in the living rooms and bedrooms of the subjects in the active group during the entire 12-week study duration. Childhood asthma control test, peak flow rate monitoring, and nasal symptom scores were evaluated at weeks 0, 6, and 12. RESULTS: At 12 weeks, the active group showed a trend toward an improvement of childhood asthma control test scores and mean evening peak flow rates, whereas the control group showed deterioration in the same measures. Total and daytime nasal symptoms scores significantly reduced in the active group (p = 0.001 and p = 0.011, respectively). The average indoor PM2.5 concentrations reduced by 43% (7.42 to 4.28 μg/m3) in the active group (p = 0.001). CONCLUSIONS: Intervention with air purifiers reduces indoor PM2.5 levels with significant improvements in nasal symptoms in children with allergic rhinitis in Fresno.
OBJECTIVE: Epidemiologic studies indicate that indoor air pollution is correlated with morbidity caused by allergic diseases. We evaluated the effectiveness of reducing the levels of indoor fine particulate matter <2.5 micrometer diameter (PM2.5) in Fresno, California using air purifiers on health outcomes in children with asthma and/or allergic rhinitis. METHODS: The active group (with air purifiers) and the control group consisted of eight houses each. Air purifiers were installed in the living rooms and bedrooms of the subjects in the active group during the entire 12-week study duration. Childhood asthma control test, peak flow rate monitoring, and nasal symptom scores were evaluated at weeks 0, 6, and 12. RESULTS: At 12 weeks, the active group showed a trend toward an improvement of childhood asthma control test scores and mean evening peak flow rates, whereas the control group showed deterioration in the same measures. Total and daytime nasal symptoms scores significantly reduced in the active group (p = 0.001 and p = 0.011, respectively). The average indoor PM2.5 concentrations reduced by 43% (7.42 to 4.28 μg/m3) in the active group (p = 0.001). CONCLUSIONS: Intervention with air purifiers reduces indoor PM2.5 levels with significant improvements in nasal symptoms in children with allergic rhinitis in Fresno.
Entities:
Keywords:
Air purifier; allergic rhinitis; asthma; indoor air pollution; particulate matter
Authors: Christine James; David I Bernstein; Jennie Cox; Patrick Ryan; Christopher Wolfe; Roman Jandarov; Nicholas Newman; Reshmi Indugula; Tiina Reponen Journal: Indoor Air Date: 2019-12-08 Impact factor: 5.770
Authors: Yoshiko Yoda; Kenji Tamura; Sho Adachi; Naruhito Otani; Shoji F Nakayama; Masayuki Shima Journal: Int J Environ Res Public Health Date: 2020-05-23 Impact factor: 3.390
Authors: Nelson Augusto Rosário Filho; Marilyn Urrutia-Pereira; Gennaro D'Amato; Lorenzo Cecchi; Ignacio J Ansotegui; Carmen Galán; Anna Pomés; Margarita Murrieta-Aguttes; Luis Caraballo; Philip Rouadi; Herberto J Chong-Neto; David B Peden Journal: World Allergy Organ J Date: 2021-01-07 Impact factor: 4.084
Authors: Sungroul Kim; Jungeun Lee; Sujung Park; Guillaume Rudasingwa; Sangwoon Lee; Sol Yu; Dae Hyun Lim Journal: Int J Environ Res Public Health Date: 2020-10-21 Impact factor: 3.390