| Literature DB >> 277233 |
V D Courtenay, I E Smith, G G Steel.
Abstract
An enhancing effect of misonidazole on the in vivo radiation response of clonogenic human tumour cells from a pancreatic carcinoma xenograft has been demonstrated using both a soft agar in vitro assay and an agar in diffusion chamber assay. Enhancement ratios of 1.8 and 1.3 were found when cells were assayed at 0 h and 18 h respectively after irradiation. No enhancement was seen with in vitro irradiation of oxygenated cells. The potential of these assay systems as a perclinical screening test for new radiosensitizers is discussed.Entities:
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Year: 1978 PMID： 277233 PMCID： PMC2149422
Source DB: PubMed Journal: Br J Cancer Suppl ISSN： 0306-9443