Literature DB >> 27723004

[Enzymatic assays of aminoglycoside antibiotics].

F H Kayser1.   

Abstract

Adenylylating or acetylating enzymes, which are produced by grampositive and gramnegative bacteria resistant to aminoglycoside antibiotics, are useful tools in determining concentrations of aminoglycosides in patients' body fluids. Due to their accuracy, stability, versatility, fastness and inexpensiveness, enzymatic assays are the tests of choice for the routine determination of aminoglycoside concentrations.

Entities:  

Year:  1977        PMID： 27723004     DOI： 10.1007/BF01642097

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  13 in total

1.  Properties of the gentamicin acetyltransferase enzyme and application to the assay of aminoglycoside antibiotics.

Authors:  J M Broughall; D S Reeves
Journal:  Antimicrob Agents Chemother       Date:  1975-08       Impact factor: 5.191

2.  Gentamicin and gentamicin C1 in the treatment of complicated urinary tract infections: comparative study of efficacy, tolerance, and pharmacokinetics.

Authors:  A Mosegaard; P G Welling; P O Madsen
Journal:  Antimicrob Agents Chemother       Date:  1975-03       Impact factor: 5.191

3.  Enzymatic adenylylation by aminoglycoside 4'-adenylytransferase and 2"-adenylyltransferase as a means of determining concentrations of aminoglycoside antibiotics in serum.

Authors:  P Santanam; F H Kayser
Journal:  Antimicrob Agents Chemother       Date:  1976-10       Impact factor: 5.191

4.  Enzymatic assay for gentamicin and related aminoglycoside antibiotics.

Authors:  R K Holmes; J P Sanford
Journal:  J Infect Dis       Date:  1974-05       Impact factor: 5.226

Review 5.  Mechanisms of antibiotic resistance in bacteria.

Authors:  R Benveniste; J Davies
Journal:  Annu Rev Biochem       Date:  1973       Impact factor: 23.643

6.  A comparison of two methods of gentamicin assay: an enzymatic procedure and an agar diffusion technique.

Authors:  R Daigneault; M Gagné; M Brazeau
Journal:  J Infect Dis       Date:  1974-12       Impact factor: 5.226

7.  The problems of drug-resistant pathogenic bacteria. R factors: biochemical mechanisms of resistance to aminoglycoside antibiotics.

Authors:  J Davies; M Brzezinska; R Benveniste
Journal:  Ann N Y Acad Sci       Date:  1971-06-11       Impact factor: 5.691

8.  [Rapid technics for the quantitative determination of aminoglycoside antibiotics].

Authors:  F Furger; A Russi; F H Kayser
Journal:  Schweiz Med Wochenschr       Date:  1973-05-26

9.  Tobramycin adenylyltransferase: a new aminoglycoside-inactivating enzyme from Staphylococcus epidermidis.

Authors:  P Santanam; F H Kayser
Journal:  J Infect Dis       Date:  1976-08       Impact factor: 5.226

10.  Gentamicin:adenine mononucleotide transferase: partial purification, characterization, and use in the clinical quantitation of gentamicin.

Authors:  A L Smith; D H Smith
Journal:  J Infect Dis       Date:  1974-04       Impact factor: 5.226
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