Literature DB >> 27722454

Ruthenium-catalyzed direct α-alkylation of amides using alcohols.

Moreshwar Bhagwan Chaudhari1, Girish Singh Bisht1, Pooja Kumari1, Boopathy Gnanaprakasam1.   

Abstract

The highly efficient direct α-alkylation of unactivated amides has been accomplished using alcohols in the presence of the Ru-PNN catalyst (0.1 mol%) with a high turnover number. Using this approach, 2-oxindole was directly transformed into C3-alkylated 3-hydroxyindolin-2-one in one step without the use of any oxidant.

Entities:  

Year:  2016        PMID： 27722454     DOI： 10.1039/c6ob01786j

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  5 in total

1.  A nickel phosphide nanoalloy catalyst for the C-3 alkylation of oxindoles with alcohols.

Authors:  Shu Fujita; Kohei Imagawa; Sho Yamaguchi; Jun Yamasaki; Seiji Yamazoe; Tomoo Mizugaki; Takato Mitsudome
Journal:  Sci Rep       Date:  2021-05-21       Impact factor: 4.379

2.  Manganese-Catalyzed α-Alkylation of Ketones, Esters, and Amides Using Alcohols.

Authors:  Subrata Chakraborty; Prosenjit Daw; Yehoshoa Ben David; David Milstein
Journal:  ACS Catal       Date:  2018-10-02       Impact factor: 13.084

3.  Iron-Catalyzed Borrowing Hydrogen C-Alkylation of Oxindoles with Alcohols.

Authors:  Mubarak B Dambatta; Kurt Polidano; Alexander D Northey; Jonathan M J Williams; Louis C Morrill
Journal:  ChemSusChem       Date:  2019-05-07       Impact factor: 8.928

4.  Electrochemical Umpolung C-H Functionalization of Oxindoles.

Authors:  Miryam Pastor; Marie Vayer; Harald Weinstabl; Nuno Maulide
Journal:  J Org Chem       Date:  2021-12-28       Impact factor: 4.354

5.  The key role of the latent N-H group in Milstein's catalyst for ester hydrogenation.

Authors:  John Pham; Cole E Jarczyk; Eamon F Reynolds; Sophie E Kelly; Thao Kim; Tianyi He; Jason M Keith; Anthony R Chianese
Journal:  Chem Sci       Date:  2021-05-24       Impact factor: 9.825
  5 in total

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