| Literature DB >> 27722410 |
R Beltran1, S Nocquet-Thibault1, F Blanchard1, R H Dodd1, K Cariou1.
Abstract
The regioselective ethoxyiodination of enamides was developed using PIFA in combination with potassium iodide in ethanol. The reaction proceeds regioselectively with excellent yields and diastereoselectivities, providing valuable synthons for further functionalisations. Control experiments were conducted, indicating that the transformation occurs through an ionic manifold involving an in situ generated hypoiodite species.Entities:
Year: 2016 PMID： 27722410 DOI： 10.1039/c6ob01673a
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876