| Literature DB >> 27722269 |
Beata Klejevskaja1, Alice L B Pyne2, Matthew Reynolds3, Arun Shivalingam3, Richard Thorogate2, Bart W Hoogenboom4, Liming Ying5, Ramon Vilar1.
Abstract
We have developed self-assembled DNA mini-circles that contain a G-quadruplex-forming sequence from the c-Myc oncogene promoter and demonstrate by FRET that the G-quadruplex unfolding kinetics are 10-fold slower than for the simpler 24-mer G-quadruplex that is commonly used for FRET experiments.Entities:
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Year: 2016 PMID： 27722269 DOI： 10.1039/c6cc07110d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222