Literature DB >> 27721006

Obesity, Vascular Disease, and Lumbar Disk Degeneration: Associations of Comorbidities in Low Back Pain.

Rebecca Wilson Zingg1, Richard Kendall2.   

Abstract

Low back pain and obesity are both rising epidemics. This article will examine global trends in obesity, contributory lifestyle and societal factors, and morbidity and mortality associated with cardiovascular disease. With this background information, this article will explore the complex physiological process of atherosclerosis and the association between impaired lumbar perfusion and low back pain. It also will provide specific guidance on exercise and nutrition to help treat these potential underlying and contributory mechanisms of spine pathology. Collectively, the article will highlight the necessity of a broader prescriptive to treat the epidemic of low back pain ideally. LEVEL OF EVIDENCE: Not applicable.
Copyright © 2017 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27721006     DOI: 10.1016/j.pmrj.2016.09.011

Source DB:  PubMed          Journal:  PM R        ISSN: 1934-1482            Impact factor:   2.298


  7 in total

1.  Orientin downregulating oxidative stress-mediated endoplasmic reticulum stress and mitochondrial dysfunction through AMPK/SIRT1 pathway in rat nucleus pulposus cells in vitro and attenuated intervertebral disc degeneration in vivo.

Authors:  Zhao Zhang; Jingtao Wu; Cheng Teng; Jinquan Wang; Jiapei Yu; Chen Jin; Libo Wang; Long Wu; Zhen Lin; Ziping Yu; Zhongke Lin
Journal:  Apoptosis       Date:  2022-09-20       Impact factor: 5.561

2.  HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy.

Authors:  Ruijun He; Zhe Wang; Min Cui; Sheng Liu; Wei Wu; Mo Chen; Yongchao Wu; Yanji Qu; Hui Lin; Sheng Chen; Baichuan Wang; Zengwu Shao
Journal:  Autophagy       Date:  2021-01-18       Impact factor: 16.016

3.  Associations between Obesity and Spinal Diseases: A Medical Expenditure Panel Study Analysis.

Authors:  Binwu Sheng; Chaoling Feng; Donglan Zhang; Hugh Spitler; Lu Shi
Journal:  Int J Environ Res Public Health       Date:  2017-02-13       Impact factor: 3.390

4.  Association between serum lipids and low back pain among a middle-aged Japanese population: a large-scale cross-sectional study.

Authors:  Takahiko Yoshimoto; Hirotaka Ochiai; Takako Shirasawa; Satsue Nagahama; Mariko Kobayashi; Akira Minoura; Ayako Miki; Yingli Chen; Hiromi Hoshino; Akatsuki Kokaze
Journal:  Lipids Health Dis       Date:  2018-11-24       Impact factor: 3.876

Review 5.  Leptin and Associated Mediators of Immunometabolic Signaling: Novel Molecular Outcome Measures for Neurostimulation to Treat Chronic Pain.

Authors:  Thomas M Kinfe; Michael Buchfelder; Shafqat R Chaudhry; Krishnan V Chakravarthy; Timothy R Deer; Marc Russo; Peter Georgius; Rene Hurlemann; Muhammad Rasheed; Sajjad Muhammad; Thomas L Yearwood
Journal:  Int J Mol Sci       Date:  2019-09-24       Impact factor: 5.923

6.  Single-Cell RNA-Seq Analysis Reveals Macrophage Involved in the Progression of Human Intervertebral Disc Degeneration.

Authors:  Zemin Ling; Yong Liu; Zhe Wang; Ziji Zhang; Bolin Chen; Jiaming Yang; Baozhu Zeng; Yu Gao; Chang Jiang; Yulin Huang; Xuenong Zou; Xiuhui Wang; Fuxin Wei
Journal:  Front Cell Dev Biol       Date:  2022-02-28

7.  Distribution Patterns of Degeneration of the Lumbar Spine in a Cohort of 200 Patients with an Indication for Lumbar MRI.

Authors:  Philipp Näther; Jan Felix Kersten; Ingmar Kaden; Kemal Irga; Albert Nienhaus
Journal:  Int J Environ Res Public Health       Date:  2022-03-21       Impact factor: 3.390

  7 in total

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