Temperature-dependent effects on the replication and transmission of arthropod-borne viruses in their insect hosts.

The transmissibility of vector borne viruses can be affected by a combination of factors, both extrinsic (climatic changes, temperature, urbanization, among others) and intrinsic (genetics, life span, immunity, among others). Temperature is of particular importance since the insect vectors of arthropod-borne viruses (arboviruses) are ectothermic and acutely susceptible to temperature changes. Modeling suggests that with increasing global temperature and urbanization, arboviral diseases will continue to emerge or reemerge. This review highlights current literature regarding temperature-dependent effects on virus-vector interactions and their potential to influence the transmission dynamics and epidemiology of arboviral diseases. Published by Elsevier Inc.