Literature DB >> 27718020

Prediction of in-hospital mortality and morbidity using high-sensitivity C-reactive protein after burr hole craniostomy.

Jung Ju Choi1, Hong Soon Kim1, Kyung Cheon Lee1, Hojin Hur1, Youn Yi Jo2.   

Abstract

BACKGROUND: The purpose of this study was to assess whether preanesthetic laboratory values can predict in-hospital mortality and morbidity in patients who have undergone burr hole craniostomy due to chronic subdural hematoma.
METHODS: From January 2007 to February 2016, the records of 502 consecutive patients who underwent burr hole craniotomy were analyzed. All cases of burr hole craniostomy were fitted with a drain, as required by our institutional protocol.
RESULTS: Patients' demographic data and preoperative laboratory values were subjected to logistic regression analysis to predict in-hospital mortality and morbidity after burr hole craniostomy. Hemoglobin, prothrombin time, activated partial thromboplastin time, serum glucose, and high-sensitivity C-reactive protein (hsCRP) were found to be significantly associated with in-hospital mortality and morbidity by univariate regression analysis, but of these, only hsCRP (hazard ratio 1.210, 95 % confidence interval 1.089-1.345, P < 0.001) was found to significantly predict in-hospital mortality and morbidity by multivariate regression analysis. Areas under the curve for predicting in-hospital mortality and morbidity were 0.765 (95 % confidence interval 0.624-0.906, P = 0.002) and 0.646 (0.559-0.733, P = 0.001), respectively.
CONCLUSIONS: Preoperative hsCRP was found to be an independent predictor of in-hospital mortality and morbidity after burr hole craniostomy due to chronic subdural hematoma.

Entities:  

Keywords:  Burr hole craniostomy; Chronic subdural hematoma; High-sensitivity C-reactive protein; Morbidity; Mortality

Mesh:

Substances:

Year:  2016        PMID: 27718020     DOI: 10.1007/s00540-016-2259-1

Source DB:  PubMed          Journal:  J Anesth        ISSN: 0913-8668            Impact factor:   2.078


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