| Literature DB >> 27717604 |
Ö Ergönül1, M Aydin2, A Azap3, S Başaran4, S Tekin5, Ş Kaya6, S Gülsün6, G Yörük7, E Kurşun8, A Yeşilkaya9, F Şimşek10, E Yılmaz11, H Bilgin12, Ç Hatipoğlu13, H Cabadak14, Y Tezer14, T Togan15, I Karaoğlan16, A İnan17, A Engin18, H E Alışkan8, S Ş Yavuz4, Ş Erdinç13, L Mulazimoglu12, Ö Azap9, F Can5, H Akalın11, F Timurkaynak2.
Abstract
This article describes the prevalence of antibiotic resistance and predictors of mortality for healthcare-associated (HA) Gram-negative bloodstream infections (GN-BSI). In total, 831 cases of HA GN-BSI from 17 intensive care units in different centres in Turkey were included; the all-cause mortality rate was 44%. Carbapenem resistance in Klebsiella pneumoniae was 38%, and the colistin resistance rate was 6%. Multi-variate analysis showed that age >70 years [odds ratio (OR) 2, 95% confidence interval (CI) 1.22-3.51], central venous catheter use (OR 2.1, 95% CI 1.09-4.07), ventilator-associated pneumonia (OR 1.9, 95% CI 1.1-3.16), carbapenem resistance (OR 1.8, 95% CI 1.11-2.95) and APACHE II score (OR 1.1, 95% CI 1.07-1.13) were significantly associated with mortality. Copyright ÂEntities:
Keywords: Bloodstream; Gram-negative; Healthcare
Mesh：
Year: 2016 PMID： 27717604 DOI： 10.1016/j.jhin.2016.08.012
Source DB: PubMed Journal: J Hosp Infect ISSN： 0195-6701 Impact factor: 3.926