Shariq Najeeb1, Zohaib Khurshid2, Sana Zohaib3, Bilal Najeeb4, Saad Bin Qasim5, Muhammad Sohail Zafar6. 1. Restorative Dental Sciences, Al Farabi Colleges, Riyadh, Saudi Arabia. 2. Department of Prosthodontics and Implantology, College of Dentistry, King Faisal University, Al-Ahsa, Saudi Arabia. 3. Department of Biomedical Engineering, College of Engineering, King Faisal University, Al-Ahsa, Saudi Arabia. 4. School of Dentistry, Riyadh College of Dentistry and Pharmacy, Riyadh, Saudi Arabia. 5. Department of Materials Science and Engineering, Kroto Research Institute, University of Sheffield, Sheffield, United Kingdom. 6. Restorative Dentistry Department, College of Dentistry, Taibah University, Madinah Munawarrah, Saudi Arabia. Electronic address: drsohail_78@hotmail.com.
Abstract
BACKGROUND AND OBJECTIVE: The exact etiology of recurrent aphthous ulcers (RAS) is unknown. The management of RAS is not always straightforward. The aim of this review is to critically analyze and summarize the clinical literature focusing on the management of aphthous ulcers using low-level lasers. MATERIALS AND METHODS: The Medline (PubMed), Web of Knowledge (ISI), Cochrane Central Register of Controlled Trials (CENTRAL) and Embase databases were searched electronically for studies published in last 20 years (1995-2015) using the keywords "recurrent aphthous stomatitis," "aphthous ulcers," and "laser." RESULTS: A total of 85 articles were found during the initial search; 76 studies were excluded for not fulfilling the criteria whereas nine studies were deemed suitable for this review. Among the included studies, two articles were case reports and seven were randomized clinical trials. Study design, sample size, type of intervention and control of each study were critically analyzed and summarized according to the CONSORT protocol. In majority of the patients, immediate pain relief and accelerated ulcer healing was observed following irradiation with lasers. CONCLUSIONS: Although various types of lasers have succeeded in providing immediate pain relief to patients, carbon dioxide (CO2) lasers have the unique advantage of requiring a short exposure time (5-10s). In order to ascertain the efficacy of laser for treating ulcers in the clinical setting, more clinical trials are required. Copyright Â
BACKGROUND AND OBJECTIVE: The exact etiology of recurrent aphthous ulcers (RAS) is unknown. The management of RAS is not always straightforward. The aim of this review is to critically analyze and summarize the clinical literature focusing on the management of aphthous ulcers using low-level lasers. MATERIALS AND METHODS: The Medline (PubMed), Web of Knowledge (ISI), Cochrane Central Register of Controlled Trials (CENTRAL) and Embase databases were searched electronically for studies published in last 20 years (1995-2015) using the keywords "recurrent aphthous stomatitis," "aphthous ulcers," and "laser." RESULTS: A total of 85 articles were found during the initial search; 76 studies were excluded for not fulfilling the criteria whereas nine studies were deemed suitable for this review. Among the included studies, two articles were case reports and seven were randomized clinical trials. Study design, sample size, type of intervention and control of each study were critically analyzed and summarized according to the CONSORT protocol. In majority of the patients, immediate pain relief and accelerated ulcer healing was observed following irradiation with lasers. CONCLUSIONS: Although various types of lasers have succeeded in providing immediate pain relief to patients, carbon dioxide (CO2) lasers have the unique advantage of requiring a short exposure time (5-10s). In order to ascertain the efficacy of laser for treating ulcers in the clinical setting, more clinical trials are required. Copyright Â
Authors: Mohammed Khaleel Ahmed; Mohammed Jafer; Maryam Nayeem; Ibtisam Hussain Moafa; Mir Furruq Ali Quadri; Hema Gopalaiah; Mir Faeq Ali Quadri Journal: J Multidiscip Healthc Date: 2020-11-18
Authors: Jun Hui Wang; Kuan Yang; Bai Ze Zhang; Zhi Fei Zhou; Zi Rui Wang; Xin Ge; Lu Lu Wang; Yu Jiang Chen; Xiao Jing Wang Journal: BMC Oral Health Date: 2020-11-10 Impact factor: 2.757