Literature DB >> 27717124

Is colorectal surgery beyond the age of 80 still feasible with acceptable mortality? An analysis of the predictive value of CR-POSSUM and life expectancy after hospital discharge.

A de Buck van Overstraeten1, J Stijns1, A Laenen2, S Fieuws2, A M Wolthuis1, A D'Hoore1.   

Abstract

AIM: Increased morbidity and mortality could mitigate the positive effect of surgery in elderly patients undergoing colorectal resections. This retrospective study aims to describe early morbidity and mortality together with long-term survival in octogenarians and nonagenarians undergoing colorectal surgery. Predictors for in-hospital mortality are identified. The predictive value of CR-POSSUM is assessed.
METHOD: Data on consecutive patients 80 years old or more undergoing a colorectal resection in our centre from 2004 until 2010 were analysed.
RESULTS: Some 286 patients [median age 84 years; interquartile range (IQR) 81.6-86.1; 133 men, 47%] underwent a colorectal resection. Median follow-up was 32 months (IQR 14.5-51.2). Two hundred and fifty-eight patients (90%) were operated on for malignancy. Only 64 patients (22.4%) underwent a laparoscopic procedure. Overall median hospital stay was 12 days (IQR 9.0-20.0) and in-hospital mortality was 9.4%. Seventy-six per cent (n = 170) of patients could return home after discharge. The 1-year survival rate was 78.6% (95% CI 73.8-82.7). Median CR-POSSUM for in-hospital mortality was 12.6% (IQR 11.9-21.0). The concordance probability estimate was 0.668 (95% CI 0.609-0.728), reflecting a moderate predictive capacity of CR-POSSUM. Once patients had been discharged from hospital, life expectancy was similar to that of the Belgian general population.
CONCLUSION: Colorectal surgery in octogenarians and nonagenarians resulted in a considerable in-hospital mortality of about 9%. One-year mortality added an additional 12%, which is in concordance with the overall life expectancy at that age. Colorectal Disease
© 2016 The Association of Coloproctology of Great Britain and Ireland.

Entities:  

Keywords:  CR-POSSUM; colorectal surgery; mortality; surgery in elderly

Mesh:

Year:  2017        PMID: 27717124     DOI: 10.1111/codi.13539

Source DB:  PubMed          Journal:  Colorectal Dis        ISSN: 1462-8910            Impact factor:   3.788


  1 in total

1.  Postoperative mortality risk assessment in colorectal cancer: development and validation of a clinical prediction model using data from the Dutch ColoRectal Audit.

Authors:  Lindsey C F de Nes; Gerjon Hannink; Jorine 't Lam-Boer; Niek Hugen; Rob H Verhoeven; Johannes H W de Wilt
Journal:  BJS Open       Date:  2022-03-08
  1 in total

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