Literature DB >> 27716504

PIWI Takes a Giant Step.

Yibei Xiao1, Ailong Ke2.   

Abstract

piRNA guides the action of PIWI proteins to silence deleterious transposons in animal reproductive tissues. Biogenesis of piRNA-induced silencing complex (piRISC) involves a multi-step process. In this issue, Matsumoto et al. report the first crystal structure of a PIWI-clade protein displaying a guide RNA, ready for action.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27716504     DOI： 10.1016/j.cell.2016.09.043

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  3 in total

1.  Structural insights into the sequence-specific recognition of Piwi by Drosophila Papi.

Authors:  Yuhan Zhang; Weiwei Liu; Ronghong Li; Jiaqi Gu; Ping Wu; Chao Peng; Jinbiao Ma; Ligang Wu; Yang Yu; Ying Huang
Journal:  Proc Natl Acad Sci U S A       Date:  2018-03-12       Impact factor: 11.205

Review 2.  PIWI-Interacting RNAs (piRNAs): Promising Applications as Emerging Biomarkers for Digestive System Cancer.

Authors:  Aiting Cai; Yuhao Hu; Zhou Zhou; Qianyi Qi; Yixuan Wu; Peixin Dong; Lin Chen; Feng Wang
Journal:  Front Mol Biosci       Date:  2022-01-27

3.  PIWI-Interacting RNA Pathway Genes: Potential Biomarkers for Clear Cell Renal Cell Carcinoma.

Authors:  Baoli Heng; Xuexia Xie; Wenjuan Zeng; Haomin Li; Liping Shi; Wencai Ye; Fanyu Wu
Journal:  Dis Markers       Date:  2022-03-01       Impact factor: 3.434
  3 in total

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