Literature DB >> 27715604

Impact of single anaerobic exercise on delayed activation of endothelial xanthine oxidase in men and women.

Magdalena Wiecek1, Marcin Maciejczyk1, Jadwiga Szymura2, Malgorzata Kantorowicz3, Zbigniew Szygula4.   

Abstract

OBJECTIVES: The aim of the study was to evaluate the activity of xanthine oxidase (XO) in the blood of men and women during the first hour following a single anaerobic exercise (AN-EX), and after 24 hours of recovery, and to determine whether the changes in XO activity in the blood after AN-EX are dependent on anaerobic performance.
METHODS: Ten men and ten women performed a single AN-EX. Blood was collected before and five times after completion of the AN-EX. The activity of XO was determined.
RESULTS: In both groups, a significant (P < 0.05) increase in blood XO activity was found only 24 hours after the AN-EX. The increased activity of XO in men was significantly lower than in women (P < 0.05). Negative correlations were found between the increase in XO activity in the blood plasma 24 hours after the AN-EX and anaerobic power, the total work performed during the AN-EX and the power decrease. DISCUSSION: In the first hour after the single AN-EX, XO activity in the blood of women and men did not change, but after 24 hours of recovery, it was significantly higher compared to baseline levels in both sexes. Single AN-EX causes a smaller increase in XO activity in people with higher anaerobic performance.

Entities:  

Keywords:  Xanthine oxidase; anaerobic exercise; muscle injuries; oxidative stress; sex differences

Mesh:

Substances:

Year:  2016        PMID: 27715604      PMCID: PMC6837425          DOI: 10.1080/13510002.2016.1238991

Source DB:  PubMed          Journal:  Redox Rep        ISSN: 1351-0002            Impact factor:   4.412


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