Literature DB >> 27715380

Ocular Manifestations, Conventional Fundus Fluorescein Angiographic Findings, and Relationship Between Angiographic Findings and Visual Acuity in Behçet's Disease.

Fatemeh Bazvand1, Mohammad Zarei1, Nazanin Ebrahimiadib2, Reza Karkhaneh1, Samaneh Davoudi2, Mahyar Soleimanzadeh1, Elaheh Sharifian1, Ramak Roohipoor1, Bobeck S Modjtahedi2.   

Abstract

PURPOSE: Evaluating the ocular manifestation and fundus fluorescein angiography (FA) findings of patients with Behçet's disease as well as the relationship between visual acuity and angiographic findings.
METHODS: Retrospective chart review of patients with Behçet's disease seen at the Farabi Eye Hospital.
RESULTS: Forty-six patients (92 eyes) with mean age of 33.41 ± 10.67 were included. The most frequent presenting symptom and sign were reduced vision (76%) and uveitis (87%), respectively. Panuveitis was the most frequent type of uveitis (76%). Among patients with FA, vasculitis was the most common finding (87%) and it was significantly more severe among patients with visual acuity less than 20/200. Macular leakage (P = 0.001), arterial narrowing (P = 0.000), and posterior retinal vasculitis (P = 0.002) on FA were all associated with worsening final visual acuity.
CONCLUSION: The most common ocular findings in Behçet's disease were panuveitis and vasculitis. Location of vasculitis, arterial narrowing, and macular leakage on initial FA may predict visual prognosis.

Entities:  

Keywords:  Autoimmune disease; macular edema; papillitis; uveitis; vasculitis

Mesh:

Year:  2016        PMID: 27715380     DOI: 10.1080/08820538.2016.1178310

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN: 0882-0538            Impact factor:   1.975


  6 in total

1.  Retinal vascular inflammatory and occlusive changes in infectious and non-infectious uveitis.

Authors:  Toshikatsu Kaburaki; Hisako Fukunaga; Rie Tanaka; Hisae Nakahara; Hidetoshi Kawashima; Shintaro Shirahama; Hidetomo Izawa; Keiko Komae; Mitsuko Takamoto; Hirotsugu Soga; Makoto Aihara
Journal:  Jpn J Ophthalmol       Date:  2020-02-03       Impact factor: 2.447

2.  Long-Term Outcomes of Behçet's Syndrome-Related Uveitis: A Monocentric Italian Experience.

Authors:  Jurgen Sota; Luca Cantarini; Antonio Vitale; Arianna Sgheri; Stefano Gentileschi; Valeria Caggiano; Viviana Gelardi; Bruno Frediani; Gian Marco Tosi; Claudia Fabiani
Journal:  Mediators Inflamm       Date:  2020-05-15       Impact factor: 4.711

3.  Behçet's Uveitis: Current Diagnostic and Therapeutic Approach

Authors:  Pınar Çakar Özdal
Journal:  Turk J Ophthalmol       Date:  2020-06-27

4.  Spectral domain optical coherence tomography as an adjunctive tool for screening Behçet uveitis.

Authors:  Hae Min Kang; Hyoung Jun Koh; Sung Chul Lee
Journal:  PLoS One       Date:  2018-12-11       Impact factor: 3.240

Review 5.  Macular edema associated with non-infectious uveitis: pathophysiology, etiology, prevalence, impact and management challenges.

Authors:  Horace Massa; Spyros Y Pipis; Georgios D Panos; Temilade Adewoyin; Athanasios Vergados; Sudeshna Patra
Journal:  Clin Ophthalmol       Date:  2019-09-10

6.  Peripapillary optical coherence tomography as an alternative to fluorescein angiography for monitoring Behcet's retinal vasculitis.

Authors:  Mohammad Zarei; Hossein Pesarakli; Mehdi Yaseri; Hamed Etesali; Nazanin Ebrahimiadib
Journal:  Sci Rep       Date:  2021-10-08       Impact factor: 4.379

  6 in total

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