Literature DB >> 27714559

CaCO3 supplementation alleviates the inhibition of formic acid on acetone/butanol/ethanol fermentation by Clostridium acetobutylicum.

Gaoxiang Qi1,2,3,4,5, Lian Xiong1,2,3,4, Xiaoqing Lin1,2,3,4, Chao Huang1,2,3,4, Hailong Li1,2,3,4, Xuefang Chen1,2,3,4, Xinde Chen6,7,8,9,10.   

Abstract

OBJECTIVE: To investigate the inhibiting effect of formic acid on acetone/butanol/ethanol (ABE) fermentation and explain the mechanism of the alleviation in the inhibiting effect under CaCO3 supplementation condition.
RESULTS: From the medium containing 50 g sugars l-1 and 0.5 g formic acid l-1, only 0.75 g ABE l-1 was produced when pH was adjusted by KOH and fermentation ended prematurely before the transformation from acidogenesis to solventogenesis. In contrast, 11.4 g ABE l-1 was produced when pH was adjusted by 4 g CaCO3 l-1. The beneficial effect can be ascribed to the buffering capacity of CaCO3. Comparative analysis results showed that the undissociated formic acid concentration and acid production coupled with ATP and NADH was affected by the pH buffering capacity of CaCO3. Four millimole undissociated formic acid was the threshold at which the transformation to solventogenesis occurred.
CONCLUSION: The inhibiting effect of formic acid on ABE fermentation can be alleviated by CaCO3 supplementation due to its buffering capacity.

Entities:  

Keywords:  Acetone/butanol/ethanol fermentation; Acid crash; Calcium carbonate; Clostridium acetobutylicum; Formic acid; Lignocellulosic hydrolysate; PH adjustment methods

Mesh:

Substances:

Year:  2016        PMID: 27714559     DOI: 10.1007/s10529-016-2231-z

Source DB:  PubMed          Journal:  Biotechnol Lett        ISSN: 0141-5492            Impact factor:   2.461


  3 in total

Review 1.  Repurposing anaerobic digestate for economical biomanufacturing and water recovery.

Authors:  Santosh Kumar; Roy Posmanik; Sabrina Spatari; Victor C Ujor
Journal:  Appl Microbiol Biotechnol       Date:  2022-02-05       Impact factor: 4.813

2.  Effect of lignocellulose-derived weak acids on butanol production by Clostridium acetobutylicum under different pH adjustment conditions.

Authors:  Jianhui Wang; Hongyan Yang; Gaoxaing Qi; Xuecheng Liu; Xu Gao; Yu Shen
Journal:  RSC Adv       Date:  2019-01-15       Impact factor: 4.036

3.  Reassessment of the role of CaCO3 in n-butanol production from pretreated lignocellulosic biomass by Clostridium acetobutylicum.

Authors:  Zengping Su; Fengqin Wang; Yaohuan Xie; Hui Xie; Guotao Mao; Hongsen Zhang; Andong Song; Zhanying Zhang
Journal:  Sci Rep       Date:  2020-10-21       Impact factor: 4.379

  3 in total

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