Literature DB >> 27714234

Double heteroannulation of S,N-acetals: a facile access to quinolone derivatives.

Manojkumar Janni1, Sahil Arora1, S Peruncheralathan1.   

Abstract

A rapid construction of quinolone fused heterocycles from single S,N-acetal precursors via double heteroannulation is described. The base, radical and metal-mediated reactions can control the C-N, C-S and C-O bond formations of the S,N-acetal with high chemoselectivity.

Entities:  

Year:  2016        PMID： 27714234     DOI： 10.1039/c6ob01568a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

Review 1.  A review on the synthesis of heteroannulated quinolones and their biological activities.

Authors:  Yaseen A M M Elshaier; Ashraf A Aly; Mohamed Abd El-Aziz; Hazem M Fathy; Alan B Brown; Mohamed Ramadan
Journal:  Mol Divers       Date:  2021-10-26       Impact factor: 3.364

2.  Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products.

Authors:  Stephen M Geddis; Teodora Coroama; Suzanne Forrest; James T Hodgkinson; Martin Welch; David R Spring
Journal:  Beilstein J Org Chem       Date:  2018-10-19       Impact factor: 2.883
  2 in total

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