Literature DB >> 27711061

Blocking fatty acid synthesis reduces lung tumor growth in mice.

Jiyeon Kim1, Ralph J DeBerardinis1.   

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Year:  2016        PMID： 27711061     DOI： 10.1038/nm.4195

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  10 in total

1.  Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.

Authors:  Mahesh S Padanad; Georgia Konstantinidou; Niranjan Venkateswaran; Margherita Melegari; Smita Rindhe; Matthew Mitsche; Chendong Yang; Kimberly Batten; Kenneth E Huffman; Jingwen Liu; Ximing Tang; Jaime Rodriguez-Canales; Neda Kalhor; Jerry W Shay; John D Minna; Jeffrey McDonald; Ignacio I Wistuba; Ralph J DeBerardinis; Pier Paolo Scaglioni
Journal:  Cell Rep       Date:  2016-07-28       Impact factor: 9.423

2.  Oncogenic pathway signatures in human cancers as a guide to targeted therapies.

Authors:  Andrea H Bild; Guang Yao; Jeffrey T Chang; Quanli Wang; Anil Potti; Dawn Chasse; Mary-Beth Joshi; David Harpole; Johnathan M Lancaster; Andrew Berchuck; John A Olson; Jeffrey R Marks; Holly K Dressman; Mike West; Joseph R Nevins
Journal:  Nature       Date:  2005-11-06       Impact factor: 49.962

Review 3.  Increased lipogenesis in cancer cells: new players, novel targets.

Authors:  Johannes V Swinnen; Koen Brusselmans; Guido Verhoeven
Journal:  Curr Opin Clin Nutr Metab Care       Date:  2006-07       Impact factor: 4.294

4.  Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.

Authors:  Lutfi Abu-Elheiga; Martin M Matzuk; Parichher Kordari; WonKeun Oh; Tattym Shaikenov; Ziwei Gu; Salih J Wakil
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-15       Impact factor: 11.205

Review 5.  Fatty acid metabolism: target for metabolic syndrome.

Authors:  Salih J Wakil; Lutfi A Abu-Elheiga
Journal:  J Lipid Res       Date:  2008-12-01       Impact factor: 5.922

6.  Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids.

Authors:  Jurre J Kamphorst; Justin R Cross; Jing Fan; Elisa de Stanchina; Robin Mathew; Eileen P White; Craig B Thompson; Joshua D Rabinowitz
Journal:  Proc Natl Acad Sci U S A       Date:  2013-05-13       Impact factor: 11.205

7.  The polymerization of acetyl-CoA carboxylase.

Authors:  N B Beaty; M D Lane
Journal:  J Biol Chem       Date:  1983-11-10       Impact factor: 5.157

Review 8.  AMPK in Health and Disease.

Authors:  Gregory R Steinberg; Bruce E Kemp
Journal:  Physiol Rev       Date:  2009-07       Impact factor: 37.312

9.  Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models.

Authors:  Robert U Svensson; Seth J Parker; Lillian J Eichner; Matthew J Kolar; Martina Wallace; Sonja N Brun; Portia S Lombardo; Jeanine L Van Nostrand; Amanda Hutchins; Lilliana Vera; Laurie Gerken; Jeremy Greenwood; Sathesh Bhat; Geraldine Harriman; William F Westlin; H James Harwood; Alan Saghatelian; Rosana Kapeller; Christian M Metallo; Reuben J Shaw
Journal:  Nat Med       Date:  2016-09-19       Impact factor: 53.440

Review 10.  Fundamentals of cancer metabolism.

Authors:  Ralph J DeBerardinis; Navdeep S Chandel
Journal:  Sci Adv       Date:  2016-05-27       Impact factor: 14.136
  10 in total
  2 in total

Review 1.  Remodeling the blood-brain barrier microenvironment by natural products for brain tumor therapy.

Authors:  Xiao Zhao; Rujing Chen; Mei Liu; Jianfang Feng; Jun Chen; Kaili Hu
Journal:  Acta Pharm Sin B       Date:  2017-09-01       Impact factor: 11.413

Review 2.  EMT Factors and Metabolic Pathways in Cancer.

Authors:  Ilias Georgakopoulos-Soares; Dionysios V Chartoumpekis; Venetsana Kyriazopoulou; Apostolos Zaravinos
Journal:  Front Oncol       Date:  2020-04-07       Impact factor: 6.244
  2 in total

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