Literature DB >> 2771071

High-field proton magnetic resonance spectroscopy of human cerebrum obtained during surgery for epilepsy.

O A Petroff1, D D Spencer, J R Alger, J W Prichard.   

Abstract

We analyzed specimens of histologically normal human cerebrum obtained at surgery for medically refractory epilepsy using proton magnetic resonance spectroscopy. Perchloric acid extracts of anterolateral temporal lobe cortex contained greater concentrations of creatine, N-acetylaspartate, gamma-aminobutyric acid, alanine, and glutamate than the under lying white matter, which contained more acetate. Frontal and temporal lobe specimens composed of both gray and white matter failed to show statistically significant differences in the concentrations of creatine, N-acetylaspartate, alanine, aspartate gamma-aminobutyric acid, glutamate, glycine, taurine, threonine, valine, acetate, choline, beta-hydroxybutyric acid, inositols, lactate pyruvate, or succinate.

Entities:  

Mesh：

Year:  1989        PMID： 2771071     DOI： 10.1212/wnl.39.9.1197

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  31 in total

1.  Region and tissue differences of metabolites in normally aged brain using multislice 1H magnetic resonance spectroscopic imaging.

Authors:  N Schuff; F Ezekiel; A C Gamst; D L Amend; A A Capizzano; A A Maudsley; M W Weiner
Journal:  Magn Reson Med       Date:  2001-05       Impact factor: 4.668

2.  Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study.

Authors:  C Neill Epperson; Ralitza Gueorguieva; Kathryn A Czarkowski; Stephanie Stiklus; Edward Sellers; John H Krystal; Douglas L Rothman; Graeme F Mason
Journal:  Psychopharmacology (Berl)       Date:  2006-05-03       Impact factor: 4.530

Review 3.  Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin.

Authors:  O A Petroff; D L Rothman
Journal:  Mol Neurobiol       Date:  1998-02       Impact factor: 5.590

4.  Quantification of metabolites from single-voxel in vivo 1H NMR data of normal human brain by means of time-domain data analysis.

Authors:  M Ala-Korpela; J P Usenius; J Keisala; A van den Boogaart; P Vainio; J Jokisaari; S Soimakallio; R Kauppinen
Journal:  MAGMA       Date:  1995 Sep-Dec       Impact factor: 2.310

Review 5.  The 13C isotope and nuclear magnetic resonance: unique tools for the study of brain metabolism.

Authors:  G F Mason; K L Behar; J C Lai
Journal:  Metab Brain Dis       Date:  1996-12       Impact factor: 3.584

6.  Metabolism of [1-13C]glucose in a synaptosomally enriched fraction of rat cerebrum studied by 1H/13C magnetic resonance spectroscopy.

Authors:  O A Petroff; A P Burlina; J Black; J W Prichard
Journal:  Neurochem Res       Date:  1991-11       Impact factor: 3.996

7.  Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose.

Authors:  Graeme F Mason; Kitt Falk Petersen; Robin A de Graaf; Gerald I Shulman; Douglas L Rothman
Journal:  J Neurochem       Date:  2006-10-31       Impact factor: 5.372

Review 8.  Current practice in the use of MEGA-PRESS spectroscopy for the detection of GABA.

Authors:  Paul G Mullins; David J McGonigle; Ruth L O'Gorman; Nicolaas A J Puts; Rishma Vidyasagar; C John Evans; Richard A E Edden
Journal:  Neuroimage       Date:  2012-12-13       Impact factor: 6.556

9.  Quantitation of normal metabolite concentrations in six brain regions by in-vivoH-MR spectroscopy.

Authors:  Ludovico Minati; Domenico Aquino; Maria Grazia Bruzzone; Alessandra Erbetta
Journal:  J Med Phys       Date:  2010-07

10.  Proton magnetic resonance spectroscopic changes of the primary motor cortex and supplementary motor area in hemiparetic patients with corticospinal tract injury due to deep intracerebral hematoma.

Authors:  Dong Joon Yang; Byung Chul Son; Hyun-Man Baik; Sang Won Lee; Jae Hoon Sung; Bo-Young Choe
Journal:  J Korean Med Sci       Date:  2004-10       Impact factor: 2.153
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