| Literature DB >> 27709210 |
Jieon Lee1, Il-Soo Park1, Ginam Park1, Kyukwang Cho2, Hee-Sung Park2, Dal-Hee Min1.
Abstract
We present a new platform for multiplexed protein kinase activity assay using TiO2 decorated graphene oxide (GO), which is applicable to high throughput inhibitor screening. On the basis of the strong affinity of TiO2 for the phosphate group and the fluorescence quenching capability of GO, phosphorylation of substrates by protein kinases was quantitatively measured in a short time.Entities:
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Year: 2016 PMID： 27709210 DOI： 10.1039/c6cc05834e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222