Literature DB >> 27708705

Beware of delayed severe brain swelling after intracerebral haematoma in HELLP syndrome.

G Gioffrè1, P A Bodkin1, E K Labram1, A Shetty2.   

Abstract

Haemolysis, elevated liver enzymes and low platelets (HELLP) syndrome is a condition associated with increased risk of adverse outcomes during pregnancy and peripartum, including neurological complications. We report the third case in the world literature of delayed brain swelling following cerebral haemorrhage as a complication of HELLP syndrome. A 36-year-old woman in labour developed HELLP, which was complicated with intracerebral haematoma. This was evacuated, but motor impairment persisted after surgery and unfortunately the patient died unexpectedly during the 11th postoperative day. Computer tomographic brain scans documented diffuse cerebral swelling, which we think may have been caused by cerebral vasospasm. Cerebral vasospasm should always be considered when managing patients who suffered from stroke complicating HELLP syndrome. Close monitoring is advised even in later stages of recovery.

Entities:  

Keywords:  Cerebral swelling; HELLP syndrome; cerebral vasospasm; intracerebral haemorrhage

Year:  2013        PMID: 27708705      PMCID: PMC5032926          DOI: 10.1258/om.2012.110030

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  19 in total

1.  Decompressive craniectomy in traumatic brain injury: the randomized multicenter RESCUEicp study (www.RESCUEicp.com).

Authors:  P J Hutchinson; E Corteen; M Czosnyka; A D Mendelow; D K Menon; P Mitchell; G Murray; J D Pickard; E Rickels; J Sahuquillo; F Servadei; G M Teasdale; I Timofeev; A Unterberg; P J Kirkpatrick
Journal:  Acta Neurochir Suppl       Date:  2006

2.  Cerebral hemodynamics in pre-eclampsia/eclampsia syndrome.

Authors:  P Zunker; J Ley-Pozo; F Louwen; G Schuierer; W Holzgreve; E B Ringelstein
Journal:  Ultrasound Obstet Gynecol       Date:  1995-12       Impact factor: 7.299

3.  Lethal pontine hemorrhage in postpartum syndrome of hemolysis, elevated liver enzyme levels, and low platelet count.

Authors:  Lawrence A Zeidman; Aleksandar Videnovic; Lawrence P Bernstein; Chimene A Pellar
Journal:  Arch Neurol       Date:  2005-07

4.  Hydrocephalus after intraventricular hemorrhage in eclamptic woman with HELLP syndrome.

Authors:  Chikako Hirashima; Akihide Ohkuchi; Shigeki Matsubara; Mika Furukawa; Takashi Watanabe; Mitsuaki Suzuki
Journal:  Hypertens Pregnancy       Date:  2006       Impact factor: 2.108

5.  HELLP syndrome with haemaglobin vasospasm.

Authors:  J Gliemroth; U Knopp; U Kehler; R Felberbaum; G Nowak
Journal:  J Clin Neurosci       Date:  2000-01       Impact factor: 1.961

6.  Time course of vasospasm in man.

Authors:  B Weir; M Grace; J Hansen; C Rothberg
Journal:  J Neurosurg       Date:  1978-02       Impact factor: 5.115

7.  Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome)

Authors:  B M Sibai; M K Ramadan; I Usta; M Salama; B M Mercer; S A Friedman
Journal:  Am J Obstet Gynecol       Date:  1993-10       Impact factor: 8.661

8.  Spontaneous acute subdural haematoma and intracerebral haemorrhage in patient with HELLP syndrome: case report.

Authors:  H Yokota; K Miyamoto; K Yokoyama; H Noguchi; K Uyama; M Oku
Journal:  Acta Neurochir (Wien)       Date:  2009-04-24       Impact factor: 2.216

Review 9.  Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count.

Authors:  Baha M Sibai
Journal:  Obstet Gynecol       Date:  2004-05       Impact factor: 7.661

10.  Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy.

Authors:  L Weinstein
Journal:  Am J Obstet Gynecol       Date:  1982-01-15       Impact factor: 8.661

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