Literature DB >> 2770840

Digestion of killed Paracoccidioides brasiliensis by neutrophils.

M Goihman-Yahr1, A Rothenberg, A Bretaña, G Istúriz, R Rosquete, E Avila-Millán, N Viloria, N Saavedra de Borges, M Carrasquero, B Pérez de Fernández.   

Abstract

We previously described an in vitro assay showing that neutrophils (PMNs) from patients with paracoccidioidomycosis (PARA) have a specific digestive deficiency against suspensions of live Paracoccidioides brasiliensis. We now report that this defect is equally detectable against autoclaved, but not Amphotericin B-killed P. brasiliensis. The use of autoclaved suspensions facilitates the use of our in vitro assay. It might allow the development of an in vitro intradermal test for digestion of fungi. Differential digestive ability of phagocytes against live (or autoclaved) and Amphotericin-B killed fungi is of conceptual interest. It may be relevant in understanding therapeutic effect of Amphotericin B.

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Year:  1989        PMID： 2770840     DOI： 10.1007/BF00436927

Source DB:  PubMed          Journal:  Mycopathologia        ISSN： 0301-486X            Impact factor:   2.574


  10 in total

1.  Counting actively metabolizing tissue cultured cells.

Authors:  H J PHILLIPS; J E TERRYBERRY
Journal:  Exp Cell Res       Date:  1957-10       Impact factor: 3.905

2.  Elimination of Mycobacterium leprae subsequent to local in vivo activation of macrophages in lepromatous leprosy by other mycobacteria.

Authors:  J Convit; M E Pinardi; G Rodríguez Ochoa; M Ulrich; J L Avila; M Goihman
Journal:  Clin Exp Immunol       Date:  1974-06       Impact factor: 4.330

3.  Trypanosoma cruzi and American Leishmania spp: immunocytochemical localization of a laminin-like protein in the plasma membrane.

Authors:  A Bretaña; J L Avila; M Arias-Flores; M Contreras; F J Tapia
Journal:  Exp Parasitol       Date:  1986-04       Impact factor: 2.011

4.  The cell wall of fungal human pathogens: its possible role in host-parasite relationships.

Authors:  G San-Blas
Journal:  Mycopathologia       Date:  1982-09-17       Impact factor: 2.574

5.  New method for estimating digestion of Paracoccidioides brasiliensis by phagocytic cells in vitro.

Authors:  M Goihman-Yahr; E Essenfeld-Yahr; M C Albornoz; L Yarzábal; M H de Gómez; B San Martín; A Ocanto; J Convit
Journal:  J Clin Microbiol       Date:  1979-09       Impact factor: 5.948

6.  A novel method for estimating killing ability and digestion of Paracoccidioides brasiliensis by phagocytic cells in vitro.

Authors:  M Goihman-Yahr; A Rothenberg; R Rosquete; E Avila-Millán; M C de Albornoz; M H de Gómez; B San Martín; A Ocanto; J Pereira; T Molina
Journal:  Sabouraudia       Date:  1985-08

7.  Studies on plating efficiency and estimation of viability of suspensions of Paracoccidioides brasiliensis yeast cells.

Authors:  M Goihman-Yahr; L Pine; M C Albornoz; L Yarzabal; M H de Gomez; B San Martin; A Ocanto; T Molina; J Convit
Journal:  Mycopathologia       Date:  1980-07-01       Impact factor: 2.574

8.  Measurement of candidacidal activity of specific leukocyte types in mixed cell populations I. Normal, myeloperoxidase-deficient, and chronic granulomatous disease neutrophils.

Authors:  R I Lehrer
Journal:  Infect Immun       Date:  1970-07       Impact factor: 3.441

9.  A test for the determination of competency in clearing bacilli in leprosy patients.

Authors:  J Convit; J L Avila; M Goihman; M E Pinardi
Journal:  Bull World Health Organ       Date:  1972       Impact factor: 9.408

10.  Defect of in vitro digestive ability of polymorphonuclear leukocytes in paracoccidioidomycosis.

Authors:  M Goihman-Yahr; E Essenfeld-Yahr; M C de Albornoz; L Yarzábal; M H de Gómez; B San Martín; A Ocanto; F Gil; J Convit
Journal:  Infect Immun       Date:  1980-05       Impact factor: 3.441
  10 in total
  1 in total

1.  Low-level laser therapy to the mouse femur enhances the fungicidal response of neutrophils against Paracoccidioides brasiliensis.

Authors:  Eva Burger; Ana Carolina S C Mendes; Giulia M A C Bani; Maísa R P L Brigagão; Gérsika B Santos; Luiz Cosme C Malaquias; Jorge Kleber Chavasco; Liana M Verinaud; Zoilo P de Camargo; Michael R Hamblin; Felipe F Sperandio
Journal:  PLoS Negl Trop Dis       Date:  2015-02-12
  1 in total

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