Russell J de Souza1,2,3, Michael A Zulyniak4, Dipika Desai5, Mateen R Shaikh6, Natalie C Campbell4, Diana L Lefebvre4, Milan Gupta4,3, Julie Wilson7, Gita Wahi8, Stephanie A Atkinson8, Koon K Teo4, Padmaja Subbarao9, Allan B Becker10, Piushkumar J Mandhane11, Stuart E Turvey12, Malcolm R Sears4, Sonia S Anand6,4,5. 1. Departments of Clinical Epidemiology and Biostatistics, rdesouz@mcmaster.ca. 2. Department of Nutritional Sciences and. 3. Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada. 4. Medicine, and. 5. Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada. 6. Departments of Clinical Epidemiology and Biostatistics. 7. Six Nations Health Services, Ohsweken, Ontario, Canada. 8. Pediatrics, McMaster University, Hamilton, Ontario, Canada. 9. Hospital for Sick Children and Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada. 10. Department of Pediatrics and Child Health, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. 11. Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada; and. 12. British Columbia Children's Hospital and Child and Family Research Institute, Department of Pediatrics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Abstract
BACKGROUND: Canada is an ethnically diverse nation, which introduces challenges for health care providers tasked with providing evidence-based dietary advice. OBJECTIVES: We aimed to harmonize food-frequency questionnaires (FFQs) across 4 birth cohorts of ethnically diverse pregnant women to derive robust dietary patterns to investigate maternal and newborn outcomes. METHODS: The NutriGen Alliance comprises 4 prospective birth cohorts and includes 4880 Canadian mother-infant pairs of predominantly white European [CHILD (Canadian Healthy Infant Longitudinal Development) and FAMILY (Family Atherosclerosis Monitoring In earLY life)], South Asian [START (SouTh Asian birth cohoRT)-Canada], or Aboriginal [ABC (Aboriginal Birth Cohort)] origins. CHILD used a multiethnic FFQ based on a previously validated instrument designed by the Fred Hutchinson Cancer Research Center, whereas FAMILY, START, and ABC used questionnaires specifically designed for use in white European, South Asian, and Aboriginal people, respectively. The serving sizes and consumption frequencies of individual food items within the 4 FFQs were harmonized and aggregated into 36 common food groups. Principal components analysis was used to identify dietary patterns that were internally validated against self-reported vegetarian status and externally validated against a modified Alternative Healthy Eating Index (mAHEI). RESULTS: Three maternal dietary patterns were identified-"plant-based," "Western," and "health-conscious"-which collectively explained 29% of the total variability in eating habits observed in the NutriGen Alliance. These patterns were strongly associated with self-reported vegetarian status (OR: 3.85; 95% CI: 3.47, 4.29; r2 = 0.30, P < 0.001; for a plant-based diet), and average adherence to the plant-based diet was higher in participants in the fourth quartile of the mAHEI than in the first quartile (mean difference: 46.1%; r2 = 0.81, P < 0.001). CONCLUSION: Dietary data collected by using FFQs from ethnically diverse pregnant women can be harmonized to identify common dietary patterns to investigate associations between maternal dietary intake and health outcomes.
BACKGROUND: Canada is an ethnically diverse nation, which introduces challenges for health care providers tasked with providing evidence-based dietary advice. OBJECTIVES: We aimed to harmonize food-frequency questionnaires (FFQs) across 4 birth cohorts of ethnically diverse pregnant women to derive robust dietary patterns to investigate maternal and newborn outcomes. METHODS: The NutriGen Alliance comprises 4 prospective birth cohorts and includes 4880 Canadian mother-infant pairs of predominantly white European [CHILD (Canadian Healthy Infant Longitudinal Development) and FAMILY (Family Atherosclerosis Monitoring In earLY life)], South Asian [START (SouTh Asian birth cohoRT)-Canada], or Aboriginal [ABC (Aboriginal Birth Cohort)] origins. CHILD used a multiethnic FFQ based on a previously validated instrument designed by the Fred Hutchinson Cancer Research Center, whereas FAMILY, START, and ABC used questionnaires specifically designed for use in white European, South Asian, and Aboriginal people, respectively. The serving sizes and consumption frequencies of individual food items within the 4 FFQs were harmonized and aggregated into 36 common food groups. Principal components analysis was used to identify dietary patterns that were internally validated against self-reported vegetarian status and externally validated against a modified Alternative Healthy Eating Index (mAHEI). RESULTS: Three maternal dietary patterns were identified-"plant-based," "Western," and "health-conscious"-which collectively explained 29% of the total variability in eating habits observed in the NutriGen Alliance. These patterns were strongly associated with self-reported vegetarian status (OR: 3.85; 95% CI: 3.47, 4.29; r2 = 0.30, P < 0.001; for a plant-based diet), and average adherence to the plant-based diet was higher in participants in the fourth quartile of the mAHEI than in the first quartile (mean difference: 46.1%; r2 = 0.81, P < 0.001). CONCLUSION: Dietary data collected by using FFQs from ethnically diverse pregnant women can be harmonized to identify common dietary patterns to investigate associations between maternal dietary intake and health outcomes.
Authors: Luis A Rodriguez; Yichen Jin; Sameera A Talegawkar; Marcia C de Oliveira Otto; Namratha R Kandula; David M Herrington; Alka M Kanaya Journal: J Nutr Date: 2020-06-01 Impact factor: 4.798
Authors: Russell J de Souza; Meera Shanmuganathan; Amel Lamri; Stephanie A Atkinson; Allan Becker; Dipika Desai; Milan Gupta; Piush J Mandhane; Theo J Moraes; Katherine M Morrison; Padmaja Subbarao; Koon K Teo; Stuart E Turvey; Natalie C Williams; Philip Britz-McKibbin; Sonia S Anand Journal: Curr Dev Nutr Date: 2020-09-02
Authors: Sandi M Azab; Russell J de Souza; Koon K Teo; Sonia S Anand; Natalie C Williams; Jordan Holzschuher; Chris McGlory; Stuart M Philips; Philip Britz-McKibbin Journal: J Lipid Res Date: 2020-03-31 Impact factor: 5.922
Authors: Michael A Zulyniak; Russell J de Souza; Mateen Shaikh; Dipika Desai; Diana L Lefebvre; Milan Gupta; Julie Wilson; Gita Wahi; Padmaja Subbarao; Allan B Becker; Piush Mandhane; Stuart E Turvey; Joseph Beyene; Stephanie Atkinson; Katherine M Morrison; Sarah McDonald; Koon K Teo; Malcolm R Sears; Sonia S Anand Journal: BMJ Open Date: 2017-11-14 Impact factor: 2.692
Authors: Kuan-Wen Wang; Russell J de Souza; Adam Fleming; Sheila K Singh; Donna L Johnston; Shayna M Zelcer; Shahrad Rod Rassekh; Sarah Burrow; Katrin Scheinemann; Lehana Thabane; M Constantine Samaan Journal: Sci Rep Date: 2017-03-22 Impact factor: 4.379
Authors: Michael A Zulyniak; Russell J de Souza; Mateen Shaikh; Chinthanie Ramasundarahettige; Keith Tam; Natalie Williams; Dipika Desai; Diana L Lefebvre; Milan Gupta; Padmaja Subbarao; Allan B Becker; Piushkumar J Mandhane; Stuart E Turvey; Theo Moraes; Meghan B Azad; Koon K Teo; Malcolm R Sears; Sonia S Anand Journal: PLoS One Date: 2020-05-14 Impact factor: 3.240
Authors: Sandi M Azab; Russell J de Souza; Amel Lamri; Meera Shanmuganathan; Zachary Kroezen; Karleen M Schulze; Dipika Desai; Natalie C Williams; Katherine M Morrison; Stephanie A Atkinson; Koon K Teo; Philip Britz-McKibbin; Sonia S Anand Journal: BMC Med Date: 2021-11-26 Impact factor: 8.775
Authors: Adrien M Aubert; Anne Forhan; Blandine de Lauzon-Guillain; Ling-Wei Chen; Kinga Polanska; Wojciech Hanke; Agnieszka Jankowska; Sara M Mensink-Bout; Liesbeth Duijts; Matthew Suderman; Caroline L Relton; Sarah R Crozier; Nicholas C Harvey; Cyrus Cooper; Fionnuala M McAuliffe; Cecily C Kelleher; Catherine M Phillips; Barbara Heude; Jonathan Y Bernard Journal: Nutrients Date: 2019-11-08 Impact factor: 5.717
Authors: Kelsea M Drall; Catherine J Field; Andrea M Haqq; Russell J de Souza; Hein M Tun; Nadia P Morales-Lizcano; Theodore B Konya; David S Guttman; Meghan B Azad; Allan B Becker; Diana L Lefebvre; Piush J Mandhane; Theo J Moraes; Malcolm R Sears; Stuart E Turvey; Padmaja Subbarao; James A Scott; Anita L Kozyrskyj Journal: Gut Microbes Date: 2020-11-09