Paulo Sérgio Azeredo Henriques1,2,3. 1. Universidade de Brasília, Faculdade de Medicina, Programa de Graduação Ciências Médicas, Brasília DF, Brasil. 2. Universidade de Brasília, Faculdade de Medicina, Departamento de Patologia, Laboratório Interdisciplinar de Biociências e Laboratório de Pesquisa de Imunogenética e Doenças Crônico-Degenerativas, Brasília DF, Brasil. 3. Hospital Regional de Taguatinga, Unidade de Clínica Médica, Departamento Clínico de Neurofiologia, Taguatinga DF, Brasil.
Abstract
OBJECTIVE: To determine the prevalence of obstructive sleep apnea (OSA) in children with attention deficit/hyperactive disorder (ADHD) and compare amplitude and latency of the P300 potential among children with and without OSA. METHOD: Sixty-one children with ADHD underwent oddball auditory attention tests for detection of P300 (ERPs) followed by an all-night polysomnography. The children were divided in two groups, those with and without OSA. RESULTS: Significant decreased amplitude of the P300 potential was observed in children with OSA when compared with children without OSA. CONCLUSION: The study showed that sleep fragmentation as a result of OSA can exacerbate the attention disorder that characterizes ADHD, and highlights the importance of assessing the presence of OSA in the differential diagnosis of children with attention deficits.
OBJECTIVE: To determine the prevalence of obstructive sleep apnea (OSA) in children with attention deficit/hyperactive disorder (ADHD) and compare amplitude and latency of the P300 potential among children with and without OSA. METHOD: Sixty-one children with ADHD underwent oddball auditory attention tests for detection of P300 (ERPs) followed by an all-night polysomnography. The children were divided in two groups, those with and without OSA. RESULTS: Significant decreased amplitude of the P300 potential was observed in children with OSA when compared with children without OSA. CONCLUSION: The study showed that sleep fragmentation as a result of OSA can exacerbate the attention disorder that characterizes ADHD, and highlights the importance of assessing the presence of OSA in the differential diagnosis of children with attention deficits.
Authors: Santiago Ucrós; Javier A Castro-Guevara; Catherine M Hill; Jose A Castro-Rodriguez Journal: Front Pediatr Date: 2022-02-28 Impact factor: 3.418