Literature DB >> 2770455

Heat shock proteins as markers of neural injury.

M F Gonzalez1, K Shiraishi, K Hisanaga, S M Sagar, M Mandabach, F R Sharp.   

Abstract

Systemic or intracerebral injections of kainic acid induced immunoreactivity for the 72 kDa heat shock protein (HSP72) in individual neurons of the rat brain in patterns matching the known histopathology of the particular injury. HSP72 immunostaining was also induced in and around areas of infarction following experimental strokes. These results suggest that HSP72 immunocytochemistry may be used as a marker of cellular injury in the mammalian brain.

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Year:  1989        PMID： 2770455     DOI： 10.1016/0169-328x(89)90033-8

Source DB:  PubMed          Journal:  Brain Res Mol Brain Res        ISSN： 0169-328X


  32 in total

Review 1.  Expression profiling following traumatic brain injury: a review.

Authors:  Paolo G Marciano; James H Eberwine; Ramesh Ragupathi; Kathryn E Saatman; David F Meaney; Tracy K McIntosh
Journal:  Neurochem Res       Date:  2002-10       Impact factor: 3.996

2.  Distribution of 72-kDa heat-shock protein in rat brain after hyperthermia.

Authors:  Y Li; M Chopp; Y Yoshida; S R Levine
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

Review 3.  Heat shock proteins in brain ischemia: role undefined as yet.

Authors:  K Kumar
Journal:  Metab Brain Dis       Date:  1992-09       Impact factor: 3.584

4.  Induction of a heat shock gene (hsp70) in rabbit retinal ganglion cells detected by in situ hybridization with plastic-embedded tissue.

Authors:  T E Masing; S J Rush; I R Brown
Journal:  Neurochem Res       Date:  1990-12       Impact factor: 3.996

5.  Experimental pneumococcal meningitis causes central nervous system pathology without inducing the 72-kd heat shock protein.

Authors:  M G Täuber; S L Kennedy; J H Tureen; D H Lowenstein
Journal:  Am J Pathol       Date:  1992-07       Impact factor: 4.307

6.  Stress protein synthesis by crayfish CNS tissue in vitro.

Authors:  J M Rochelle; R M Grossfeld; D L Bunting; M Tytell; B E Dwyer; Z Y Xue
Journal:  Neurochem Res       Date:  1991-05       Impact factor: 3.996

7.  Time course of induction of a heat shock gene (hsp70) in the rabbit cerebellum after LSD in vivo: involvement of drug-induced hyperthermia.

Authors:  P Manzerra; I R Brown
Journal:  Neurochem Res       Date:  1990-01       Impact factor: 3.996

Review 8.  Blockade of glutamate excitotoxicity and its clinical applications.

Authors:  K Hirose; P H Chan
Journal:  Neurochem Res       Date:  1993-04       Impact factor: 3.996

9.  Nerve and skin damage in leprosy is associated with increased intralesional heat shock protein.

Authors:  S Khanolkar-Young; D B Young; M J Colston; J N Stanley; D N Lockwood
Journal:  Clin Exp Immunol       Date:  1994-05       Impact factor: 4.330

10.  Similar frequency of autoantibodies against 70-kD class heat-shock proteins in healthy subjects and systemic lupus erythematosus patients.

Authors:  I Kindås-Mügge; G Steiner; J S Smolen
Journal:  Clin Exp Immunol       Date:  1993-04       Impact factor: 4.330
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