Pawel Miotla1, Rufus Cartwright2,3, Katarzyna Skorupska1, Michal Bogusiewicz1, Ewa Markut-Miotla4, Konrad Futyma1, Tomasz Rechberger1. 1. 2nd Chair and Department of Gynaecology, Medical University of Lublin, Lublin, Poland. 2. Department of Epidemiology and Biostatistics, Imperial College London, London, UK. 3. Department of Urogynaecology, Imperial College London, London, UK. 4. Department of Paediatric Pulmonology and Rheumatology, Medical Univeristy of Lublin, Lublin, Poland.
Abstract
AIMS: Urgency urinary incontinence (UUI), and the symptoms of overactive bladder (OAB) have a negative impact on female sexual function. The aim of this study was to investigate the effect of intravesical onabotulinumtoxinA (Botox) injection on sexual function in women with OAB, using the multi domain Female Sexual Function Index (FSFI) questionnaire. METHODS: Sixty-eight sexually active women with idiopathic OAB with at least one episode of UUI and ≥8 micturitions per 24 h were recruited. Patients completed the FSFI questionnaire before and 12 weeks after treatment with intravesical onabotulinumtoxinA injections. Baseline scores were compared with a control group of age-matched healthy women. RESULTS: Fifty-six women completed the study. At baseline OAB patients reported decreased quality of sexual function in all domains measured with FSFI, in comparison to healthy women (median 21.8 vs. 26.3, P < 0.001). Over 90% of participants reported clinically relevant improvements in sexual function, with statistically significant changes in mean scores in all six domains. CONCLUSIONS: Intravesical Botox injections provide improvement in sexual function in women with OAB. Neurourol. Urodynam. 9999:XX-XX, 2016.
AIMS: Urgency urinary incontinence (UUI), and the symptoms of overactive bladder (OAB) have a negative impact on female sexual function. The aim of this study was to investigate the effect of intravesical onabotulinumtoxinA (Botox) injection on sexual function in women with OAB, using the multi domain Female Sexual Function Index (FSFI) questionnaire. METHODS: Sixty-eight sexually active women with idiopathic OAB with at least one episode of UUI and ≥8 micturitions per 24 h were recruited. Patients completed the FSFI questionnaire before and 12 weeks after treatment with intravesical onabotulinumtoxinA injections. Baseline scores were compared with a control group of age-matched healthy women. RESULTS: Fifty-six women completed the study. At baseline OABpatients reported decreased quality of sexual function in all domains measured with FSFI, in comparison to healthy women (median 21.8 vs. 26.3, P < 0.001). Over 90% of participants reported clinically relevant improvements in sexual function, with statistically significant changes in mean scores in all six domains. CONCLUSIONS: Intravesical Botox injections provide improvement in sexual function in women with OAB. Neurourol. Urodynam. 9999:XX-XX, 2016.
Authors: Matteo Frigerio; Marta Barba; Alice Cola; Andrea Braga; Angela Celardo; Gaetano Maria Munno; Maria Teresa Schettino; Primo Vagnetti; Fulvio De Simone; Alessandra Di Lucia; Giulia Grassini; Marco Torella Journal: Medicina (Kaunas) Date: 2022-04-09 Impact factor: 2.948
Authors: Sandra Mühlstädt; Shahidul Mischner; Jennifer Kranz; Petra Anheuser; Nasreldin Mohammed; Joachim A Steffens; Paolo Fornara Journal: Front Surg Date: 2018-10-16