Literature DB >> 27699495

Hubble trial: time to stick to basics for treatment of haemorrhoids?

S R Brown1.   

Abstract

The results of the Hubble trial, a randomised controlled trial comparing haemorrhoidal artery ligation with rubber band ligation for early-grade prolapsing haemorrhoids, are discussed. The difficulties in defining treatment success are debated along with the trial design highlighting the pitfalls of previous research. A finding that haemorrhoidal artery ligation is not necessarily superior to cheap alternatives has implications for current practice and future commissioning of surgeons.

Entities:  

Keywords:  Haemorrhoidal artery ligation; Haemorrhoids; Rubber band ligation

Mesh:

Year:  2016        PMID: 27699495     DOI: 10.1007/s10151-016-1535-2

Source DB:  PubMed          Journal:  Tech Coloproctol        ISSN: 1123-6337            Impact factor:   3.781


  11 in total

Review 1.  Clinical outcome following Doppler-guided haemorrhoidal artery ligation: a systematic review.

Authors:  P H Pucher; M H Sodergren; A C Lord; A Darzi; P Ziprin
Journal:  Colorectal Dis       Date:  2013-06       Impact factor: 3.788

2.  'Distal Doppler-guided dearterialization' is highly effective in treating haemorrhoids by transanal haemorrhoidal dearterialization.

Authors:  C Ratto; L Donisi; A Parello; F Litta; G Zaccone; V De Simone
Journal:  Colorectal Dis       Date:  2012-11       Impact factor: 3.788

3.  Hemorrhoidal artery ligation procedure with or without Doppler transducer in grade II and III hemorrhoidal disease: a blinded randomized clinical trial.

Authors:  Jaap-Peter Schuurman; Inne H M Borel Rinkes; Peter M N Y H Go
Journal:  Ann Surg       Date:  2012-05       Impact factor: 12.969

4.  Clinical outcomes of Doppler-guided haemorrhoidal artery ligation: a meta-analysis.

Authors:  Hong Liu; Chunmei Yang; Benhui Chen; Jing Wu; Hongbo He
Journal:  Int J Clin Exp Med       Date:  2015-04-15

5.  Development and validation of a symptom-based severity score for haemorrhoidal disease: the Sodergren score.

Authors:  P H Pucher; M Qurashi; A-M Howell; O Faiz; P Ziprin; A Darzi; M H Sodergren
Journal:  Colorectal Dis       Date:  2015-07       Impact factor: 3.788

Review 6.  Transanal hemorrhoidal dearterialization: a systematic review.

Authors:  Pasquale Giordano; John Overton; Francesco Madeddu; Sabir Zaman; Gianpiero Gravante
Journal:  Dis Colon Rectum       Date:  2009-09       Impact factor: 4.585

7.  Doppler-guided transanal haemorrhoidal dearterialization for haemorrhoids: results from a multicentre trial.

Authors:  C Ratto; A Parello; E Veronese; E Cudazzo; E D'Agostino; C Pagano; E Cavazzoni; L Brugnano; F Litta
Journal:  Colorectal Dis       Date:  2015-01       Impact factor: 3.788

8.  Randomized clinical trial of symptom control after stapled anopexy or diathermy excision for haemorrhoid prolapse.

Authors:  P-O Nyström; N Qvist; D Raahave; I Lindsey; N Mortensen
Journal:  Br J Surg       Date:  2010-02       Impact factor: 6.939

9.  Prospective evaluation of stapled haemorrhoidopexy versus transanal haemorrhoidal dearterialisation for stage II and III haemorrhoids: three-year outcomes.

Authors:  P Giordano; P Nastro; A Davies; G Gravante
Journal:  Tech Coloproctol       Date:  2011-02-12       Impact factor: 3.781

10.  A pragmatic, multicentre, randomised controlled trial comparing stapled haemorrhoidopexy to traditional excisional surgery for haemorrhoidal disease (eTHoS): study protocol for a randomised controlled trial.

Authors:  Angus J M Watson; Hanne Bruhn; Kathleen MacLeod; Alison McDonald; Gladys McPherson; Mary Kilonzo; John Norrie; Malcolm A Loudon; Kirsty McCormack; Brian Buckley; Steven Brown; Finlay Curran; David Jayne; Ramesh Rajagopal; Jonathan A Cook
Journal:  Trials       Date:  2014-11-11       Impact factor: 2.279

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