Literature DB >> 27698646

Pleomorphic Hyalinizing Angiectatic Tumor Arising in the Hand: A Case Report.

Patrick M Kane1, Michael P Gaspar1, Benjamin B Whiting1, Randall W Culp1.   

Abstract

Background: Background: Pleomorphic hyalinizing angiectatic tumors (PHATs) are extremely rare, non-metastasizing tumors of uncertain origin that are typically seen in the lower extremities. To date, it is estimated that less than 100 cases have been reported worldwide since first described in 1996.
Methods: The case of a 35-year-old male with a several-year history of a dorsal hand mass is presented. Although the patient was initially asymptomatic, in the months prior to presentation, the patient complained of pain with power grasp and direct pressure over the mass. The patient underwent uncomplicated surgical excision, during which the mass was noted to be adherent to the underlying extensor tendons.
Results: Immunopathology confirmed the mass to be PHAT. We believe this is the first documented case of this rare tumor occurring in the hand. Conclusions: History and epidemiology of PHAT are reviewed. Then, in the context of the presented case, pre-operative evaluation, surgical management, pathologic findings and post-operative follow-up are all discussed.

Entities:  

Keywords:  hand; mass; pleomorphic hyalinizing angiectatic tumor

Mesh:

Year:  2016        PMID: 27698646      PMCID: PMC5030859          DOI: 10.1177/1558944715627275

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


  10 in total

1.  Pleomorphic hyalinizing angiectatic tumor: imaging findings.

Authors:  Ty K Subhawong; Andrea P Subhawong; Elizabeth A Montgomery; Laura M Fayad
Journal:  Skeletal Radiol       Date:  2012-06-03       Impact factor: 2.199

2.  Pleomorphic hyalinizing angiectatic tumor of soft parts.

Authors:  John C Lee; Xiu Yan Jiang; Richard H S Karpinski; Eric D Moore
Journal:  Surgery       Date:  2005-01       Impact factor: 3.982

Review 3.  Pleomorphic hyalinizing angiectatic tumor of soft parts: case report with unusual ganglion-like cells and review of the literature.

Authors:  Yi-Che Changchien; Pál Bocskai; Ilona Kovács; Zoltán Hargitai; Sándor Kollár; Miklós Török
Journal:  Pathol Res Pract       Date:  2014-05-04       Impact factor: 3.250

4.  Large pleomorphic hyalinizing angiectatic tumor of the forearm: A multidisciplinary perspective.

Authors:  Philip S Brazio; Alan L Morrison; Mitch Oh; Nelson Goldberg; Cherif N Boutros
Journal:  Surgery       Date:  2015-06-04       Impact factor: 3.982

5.  Primary cutaneous myxofibrosarcoma mimicking pleomorphic hyalinizing angiectatic tumor (PHAT): a potential diagnostic pitfall.

Authors:  Takako Mitsuhashi; Ronald J Barr; Lawrence A Machtinger; David S Cassarino
Journal:  Am J Dermatopathol       Date:  2005-08       Impact factor: 1.533

6.  Pleomorphic hyalinizing angiectatic tumor: analysis of 41 cases supporting evolution from a distinctive precursor lesion.

Authors:  Andrew L Folpe; Sharon W Weiss
Journal:  Am J Surg Pathol       Date:  2004-11       Impact factor: 6.394

7.  Pleomorphic hyalinizing angiectatic tumor with a sarcomatous component recurring as high-grade myxofibrosarcoma.

Authors:  Dmitry V Kazakov; Michal Pavlovsky; Petr Mukensnabl; Michal Michal
Journal:  Pathol Int       Date:  2007-05       Impact factor: 2.534

8.  Pleomorphic hyalinizing angiectatic tumor of soft parts. A low-grade neoplasm resembling neurilemoma.

Authors:  M E Smith; C Fisher; S W Weiss
Journal:  Am J Surg Pathol       Date:  1996-01       Impact factor: 6.394

9.  Pleomorphic hyalinizing angiectatic tumor of soft parts involving the upper limb.

Authors:  Suresh Parameshwarappa; Gabriel Rodrigues; Nitin Nagpal; Lakshmi Rao
Journal:  Indian J Surg       Date:  2010-08-26       Impact factor: 0.656

10.  Pleomorphic hyalinizing angiectatic tumor arising in the thigh: A case report.

Authors:  Kayo Suzuki; Taketoshi Yasuda; Takeshi Hori; Takeshi Oya; Kenta Watanabe; Masahiko Kanamori; Tomoatsu Kimura
Journal:  Oncol Lett       Date:  2014-02-14       Impact factor: 2.967

  10 in total
  4 in total

1.  Benign Hand Tumors (Part II): Soft Tissue Tumors.

Authors:  Jonathan Lans; Kai-Lou C Yue; René M Castelein; David I Suster; G Petur Nielsen; Neal C Chen; Santiago A Lozano-Calderon
Journal:  Hand (N Y)       Date:  2020-07-15

Review 2.  Pleomorphic Hyalinizing Angiectatic Tumor (PHAT): Review of the Literature with Case Presentation.

Authors:  Gerardo Cazzato; Anna Colagrande; Antonietta Cimmino; Teresa Lettini; Maria Teresa Savino; Carmen Martella; Giuseppe Ingravallo; Leonardo Resta
Journal:  Dermatopathology (Basel)       Date:  2021-04-04

Review 3.  Pleomorphic hyalinizing angiectatic tumor of the vulva: literature review based on a rare presentation.

Authors:  Eveline Cristina da Silva; Rodrigo Fonseca Abreu; Antônio Geraldo Nascimento; Louise De Brot Andrade
Journal:  Autops Case Rep       Date:  2022-02-11

4.  Imaging and histological appearance of pleomorphic hyalinizing angiectatic tumors: A case series and literature review.

Authors:  Couger Jimenez Jaramillo; John Wojcik; Kristy Weber; Ronnie Sebro
Journal:  Oncol Lett       Date:  2018-02-02       Impact factor: 2.967

  4 in total

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