Literature DB >> 27697197

A Patient With Alcoholic Ketoacidosis and Profound Lactemia.

Ryan S Gerrity1, Anthony F Pizon2, Andrew M King3, Kenneth D Katz4, Nathan B Menke2.   

Abstract

BACKGROUND: Alcoholic ketoacidosis (AKA) is a complex syndrome that results from disrupted metabolism in the setting of excessive alcohol use and poor oral intake. Dehydration, glycogen depletion, high redox state, and release of stress hormones are the primary factors producing the characteristic anion gap metabolic acidosis with an elevated β-hydroxybutyrate (β-OH) and lactate. CASE REPORT: We present the case of a 47-year-old man who presented to the emergency department with metabolic acidosis and profoundly elevated lactate levels who had AKA. He recovered completely with intravenous fluids and parenteral glucose administration. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Emergency physicians should always consider the immediately life-threatening causes of a severe anion gap metabolic acidosis and treat aggressively based on the situation. This case highlights the fact that AKA can present with an impressively elevated lactate levels. Emergency physicians should keep AKA in the differential diagnosis of patients who present with a similar clinical picture.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  acidosis; alcohol; ketones; lactate

Mesh:

Substances:

Year:  2016        PMID: 27697197     DOI: 10.1016/j.jemermed.2015.05.048

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  2 in total

1.  Starvation ketoacidosis on the acute medical take.

Authors:  Alexander J Gall; Robert Duncan; Amit Badshah
Journal:  Clin Med (Lond)       Date:  2020-05       Impact factor: 2.659

2.  Multiple electrolyte imbalances and mixed acid-base disorder posing a diagnostic dilemma: a case report.

Authors:  Fortune O Alabi; Christopher O Alabi; Rafaela G Basso; Nadia Lakhdar; Adebanke O Oderinde
Journal:  J Med Case Rep       Date:  2020-01-20
  2 in total

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