Literature DB >> 27696879

FeCl3-Catalyzed Cross-Dehydrogenative Coupling between Imidazoheterocycles and Oxoaldehydes.

Sadhanendu Samanta1, Susmita Mondal1, Sougata Santra2, Golam Kibriya1, Alakananda Hajra1.   

Abstract

An Fe(III)-catalyzed efficient dicarbonylation of imidazoheterocycles has been developed through cross-dehydrogenative coupling between imidazoheterocycles and oxoaldehydes under ambient air in high yields. The present protocol is also applicable to indolizines. Imidazopyridine produced bisimidazopyridine with arylaldehyde. Experimental results suggest that the reactions proceed through the nonradical pathway.

Entities:  

Year:  2016        PMID: 27696879     DOI: 10.1021/acs.joc.6b02091

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Catalyst free, C-3 functionalization of imidazo[1,2-a]pyridines to rapidly access new chemical space for drug discovery efforts.

Authors:  Naresh Gunaganti; Anupreet Kharbanda; Naga Rajiv Lakkaniga; Lingtian Zhang; Rose Cooper; Hong-Yu Li; Brendan Frett
Journal:  Chem Commun (Camb)       Date:  2018-11-15       Impact factor: 6.222

2.  Dual Role of Glyoxal in Metal-Free Dicarbonylation Reaction: Synthesis of Symmetrical and Unsymmetrical Dicarbonyl Imidazoheterocycles.

Authors:  Nitesh Kumar Nandwana; Om P S Patel; Manu R Srivathsa; Anil Kumar
Journal:  ACS Omega       Date:  2019-06-11
  2 in total

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