The Bitter Chemodiversity of Hops (Humulus lupulus L.).

To map the chemodiversity of key bitter compounds in hops, a total of 75 different samples collected from the global hop market were analyzed for 117 key bitter tastants by means of a multiparametric HPLC-MS/MSMRM method. Among the compounds detected, 2'',3''-epoxyxanthohumol was detected for the first time in hops and iso¬xantho¬humol M was identified as a marker compound for varieties grown in Germany. Hop ageing experiments in the absence and presence of air oxygen, respectively, were conducted to address the stability of hop-derived compounds during long-term storage.