Literature DB >> 27696142

Contemporary Controversies in Digoxin Use in Systolic Heart Failure.

Chonyang L Albert1, Forum Kamdar1, Mazen Hanna2.   

Abstract

Digoxin remains one of the oldest therapies for heart failure; however, its safety and efficacy have been controversial since its initial use. Questions that remain include the clinical efficacy of digoxin when added to contemporary medical therapy, when and if it should be added, and how to minimize adverse effects. In this review, we will summarize recent data on the use of digoxin in systolic heart failure and address some of the controversies regarding the role of digoxin in the modern era of heart failure treatment.

Entities:  

Keywords:  Digoxin; Heart failure

Mesh：

Substances：

Year:  2016        PMID： 27696142     DOI： 10.1007/s11897-016-0302-z

Source DB:  PubMed          Journal:  Curr Heart Fail Rep        ISSN： 1546-9530


  52 in total

1.  Therapeutic ranges of serum digoxin concentrations in patients with heart failure.

Authors:  Zachary D Goldberger; Ary L Goldberger
Journal:  Am J Cardiol       Date:  2012-04-11       Impact factor: 2.778

2.  Effectiveness and safety of digoxin among contemporary adults with incident systolic heart failure.

Authors:  James V Freeman; Jingrong Yang; Sue Hee Sung; Mark A Hlatky; Alan S Go
Journal:  Circ Cardiovasc Qual Outcomes       Date:  2013-09-10

3.  Does digoxin provide additional hemodynamic and autonomic benefit at higher doses in patients with mild to moderate heart failure and normal sinus rhythm?

Authors:  M L Slatton; W N Irani; S A Hall; L G Marcoux; R L Page; P A Grayburn; E J Eichhorn
Journal:  J Am Coll Cardiol       Date:  1997-05       Impact factor: 24.094

4.  Effect of digoxin on shocks in cardiac resynchronization therapy-defibrillator patients with coronary artery disease.

Authors:  Evan Adelstein; David Schwartzman; Sandeep Jain; Raveen Bazaz; Samir Saba
Journal:  Am J Cardiol       Date:  2013-12-25       Impact factor: 2.778

5.  Temporal Trends of Digoxin Use in Patients Hospitalized With Heart Failure: Analysis From the American Heart Association Get With The Guidelines-Heart Failure Registry.

Authors:  Nish Patel; Christine Ju; Conrad Macon; Udho Thadani; Phillip J Schulte; Adrian F Hernandez; Deepak L Bhatt; Javed Butler; Clyde W Yancy; Gregg C Fonarow
Journal:  JACC Heart Fail       Date:  2016-02-10       Impact factor: 12.035

6.  The effect of gender on outcome in digitalis-treated heart failure patients.

Authors:  M Domanski; J Fleg; M Bristow; S Knox
Journal:  J Card Fail       Date:  2005-03       Impact factor: 5.712

7.  Digoxin use and heart failure outcomes: results from the Valsartan Heart Failure Trial (Val-HeFT).

Authors:  Javed Butler; Inder S Anand; Michael A Kuskowski; Thomas Rector; Peter Carson; Jay N Cohn
Journal:  Congest Heart Fail       Date:  2010 Sep-Oct

8.  Progression of mild untreated heart failure during six months follow-up and clinical and neurohumoral effects of ibopamine and digoxin as monotherapy. DIMT Study Group. Dutch Ibopamine Multicenter Trial.

Authors:  D J van Veldhuisen; J Brouwer; A J Man in 't Veld; P H Dunselman; F Boomsma; K I Lie
Journal:  Am J Cardiol       Date:  1995-04-15       Impact factor: 2.778

9.  Effect of long-term digoxin therapy on autonomic function in patients with chronic heart failure.

Authors:  H Krum; J T Bigger; R L Goldsmith; M Packer
Journal:  J Am Coll Cardiol       Date:  1995-02       Impact factor: 24.094

10.  Effects of increasing maintenance dose of digoxin on left ventricular function and neurohormones in patients with chronic heart failure treated with diuretics and angiotensin-converting enzyme inhibitors.

Authors:  M Gheorghiade; V B Hall; G Jacobsen; M Alam; H Rosman; S Goldstein
Journal:  Circulation       Date:  1995-10-01       Impact factor: 29.690
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