Literature DB >> 27692732

Variation among pathologists' treatment suggestions for melanocytic lesions: A survey of pathologists.

Kachiu C Lee1, Sue Peacock2, Martin A Weinstock3, Ge Alice Zhao4, Stevan R Knezevich5, David E Elder6, Raymond L Barnhill7, Michael W Piepkorn8, Lisa M Reisch2, Patricia A Carney9, Tracy Onega10, Jason P Lott11, Joann G Elmore12.   

Abstract

BACKGROUND: The extent of variability in treatment suggestions for melanocytic lesions made by pathologists is unknown.
OBJECTIVE: We investigated how often pathologists rendered suggestions, reasons for providing suggestions, and concordance with national guidelines.
METHODS: We conducted a cross-sectional survey of pathologists. Data included physician characteristics, experience, and treatment recommendation practices.
RESULTS: Of 301 pathologists, 207 (69%) from 10 states (California, Connecticut, Hawaii, Iowa, Kentucky, Louisiana, New Jersey, New Mexico, Utah, and Washington) enrolled. In all, 15% and 7% reported never and always including suggestions, respectively. Reasons for offering suggestions included improved care (79%), clarification (68%), and legal liability (39%). Reasons for not offering suggestions included referring physician preference (48%), lack of clinical information (44%), and expertise (29%). Training and caseload were associated with offering suggestions (P < .05). Physician suggestions were most consistent for mild/moderate dysplastic nevi and melanoma. For melanoma in situ, 18 (9%) and 32 (15%) pathologists made suggestions that undertreated or overtreated lesions based on National Comprehensive Cancer Network (NCCN) guidelines, respectively. For invasive melanoma, 14 (7%) pathologists made treatment suggestions that undertreated lesions based on NCCN guidelines. LIMITATIONS: Treatment suggestions were self-reported.
CONCLUSIONS: Pathologists made recommendations ranging in consistency. These findings may inform efforts to reduce treatment variability and optimize patterns of care delivery for patients.
Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  atypical nevi; dermatopathology; dysplastic nevi; melanocytic lesions; melanoma; melanoma in situ; treatment

Mesh:

Year:  2016        PMID: 27692732      PMCID: PMC5164851          DOI: 10.1016/j.jaad.2016.07.029

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  48 in total

Review 1.  NIH Consensus conference. Diagnosis and treatment of early melanoma.

Authors: 
Journal:  JAMA       Date:  1992-09-09       Impact factor: 56.272

2.  State of the art, nomenclature, and points of consensus and controversy concerning benign melanocytic lesions: outcome of an international workshop.

Authors:  Raymond L Barnhill; Lorenzo Cerroni; Martin Cook; David E Elder; Helmut Kerl; Philip E LeBoit; Stanley W McCarthy; Martin C Mihm; Wolter J Mooi; Michael W Piepkorn; Victor G Prieto; Richard A Scolyer
Journal:  Adv Anat Pathol       Date:  2010-03       Impact factor: 3.875

3.  NCCN melanoma practice guidelines. National Comprehensive Cancer Network.

Authors:  A Houghton; D Coit; W Bloomer; A Buzaid; D Chu; B Eisenburgh; J Guitart; T Johnson; S Miller; S Sener; K Tanabe; J Thompson; M Urist; M Walker
Journal:  Oncology (Williston Park)       Date:  1998-07       Impact factor: 2.990

4.  Surgical margins for possibly malignant melanocytic lesions.

Authors:  Landon E Stigall; John A Zitelli
Journal:  J Am Acad Dermatol       Date:  2014-09       Impact factor: 11.527

5.  Melanocytic tumors of uncertain malignant potential: results of a tutorial held at the XXIX Symposium of the International Society of Dermatopathology in Graz, October 2008.

Authors:  Lorenzo Cerroni; Raymond Barnhill; David Elder; Geoffrey Gottlieb; Peter Heenan; Heinz Kutzner; Philip E LeBoit; Martin Mihm; Juan Rosai; Helmut Kerl
Journal:  Am J Surg Pathol       Date:  2010-03       Impact factor: 6.394

6.  A multiobserver, population-based analysis of histologic dysplasia in melanocytic nevi.

Authors:  M W Piepkorn; R L Barnhill; L A Cannon-Albright; D E Elder; D E Goldgar; C M Lewis; J C Maize; L J Meyer; M S Rabkin; R W Sagebiel
Journal:  J Am Acad Dermatol       Date:  1994-05       Impact factor: 11.527

7.  Lymphatic invasion predicts aggressive behavior in melanocytic tumors of uncertain malignant potential (MELTUMP).

Authors:  Ronnie M Abraham; Giorgos Karakousis; Geza Acs; Amy F Ziober; Lorenzo Cerroni; Martin C Mihm; David E Elder; Xiaowei Xu
Journal:  Am J Surg Pathol       Date:  2013-05       Impact factor: 6.394

8.  The atypical Spitz tumor of uncertain biologic potential: a series of 67 patients from a single institution.

Authors:  Mathew W Ludgate; Douglas R Fullen; Julia Lee; Lori Lowe; Carol Bradford; James Geiger; Jennifer Schwartz; Timothy M Johnson
Journal:  Cancer       Date:  2009-02-01       Impact factor: 6.860

Review 9.  Atypical Spitz tumours and sentinel lymph node biopsy: a systematic review.

Authors:  Aimilios Lallas; Athanassios Kyrgidis; Gerardo Ferrara; Harald Kittler; Zoe Apalla; Fabio Castagnetti; Caterina Longo; Elvira Moscarella; Simonetta Piana; Iris Zalaudek; Giuseppe Argenziano
Journal:  Lancet Oncol       Date:  2014-04       Impact factor: 41.316

10.  Histopathologic diagnosis of dysplastic nevi: concordance among pathologists convened by the World Health Organization Melanoma Programme.

Authors:  C Clemente; A J Cochran; D E Elder; A Levene; R M MacKie; M C Mihm; F Rilke; N Cascinelli; T B Fitzpatrick; A J Sober
Journal:  Hum Pathol       Date:  1991-04       Impact factor: 3.466

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  3 in total

1.  Improving clinical diagnosis of early-stage cutaneous melanoma based on Raman spectroscopy.

Authors:  Inês P Santos; Remco van Doorn; Peter J Caspers; Tom C Bakker Schut; Elisa M Barroso; Tamar E C Nijsten; Vincent Noordhoek Hegt; Senada Koljenović; Gerwin J Puppels
Journal:  Br J Cancer       Date:  2018-11-09       Impact factor: 7.640

Review 2.  Molecular Biomarkers for Melanoma Screening, Diagnosis and Prognosis: Current State and Future Prospects.

Authors:  Dekker C Deacon; Eric A Smith; Robert L Judson-Torres
Journal:  Front Med (Lausanne)       Date:  2021-04-16

3.  Pathologists' agreement on treatment suggestions for melanocytic skin lesions.

Authors:  Mustufa A Jafry; Sue Peacock; Andrea C Radick; Hannah L Shucard; Lisa M Reisch; Michael W Piepkorn; Stevan R Knezevich; Martin A Weinstock; Raymond L Barnhill; David E Elder; Kathleen F Kerr; Joann G Elmore
Journal:  J Am Acad Dermatol       Date:  2019-12-17       Impact factor: 11.527

  3 in total

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