Literature DB >> 27690538

Role of diffusion weighted magnetic resonance imaging in a rat model of testicular torsion.

Furkan Ufuk1, Duygu Herek2, Özkan Herek3, Metin Akbulut4.   

Abstract

OBJECTIVE: The purpose of this study was to investigate the usefulness of diffusion-weighted imaging (DWI) in the detection of different degrees of testicular torsion (TT) at the 8th hour and testicular salvageability at the 24th hour of torsion.
METHODS: 31 rats were randomly classified into 4 groups. In Group 1 (sham-control group), the left testicle was kept outside and replaced. Left testicles were kept outside and twisted 360° in Group 2, 720° in Group 3 and 1080° in Group 4. Later, DWI was performed at 8th and 24th hours. After DWI, bilateral radical orchiectomy and histopathological examination were performed. Apparent diffusion coefficient (ADC) maps were obtained with b-factors of 0 and 800 s mm-2. Comparisons of ADC values and damage in testicles were performed with Kruskal-Wallis test.
RESULTS: Sensitivity of DWI in the diagnosis of TT was 12.5% for 360° torsion, 100% for 720° torsion and 1080° torsion at the 8th hour of torsion. Mean ADC values of the left testicles increased significantly at the 24th hour of torsion in Groups 3 and 4. All testicles in Groups 3 and 4 were observed to be irrecoverable on histopathological examination.
CONCLUSION: Increased ADC values in the affected testicle may represent irreversible tissue damage. So, immediate surgery is not required at this stage, which may reduce morbidity and mortality caused by immediate surgery and anaesthesia. Advances in knowledge: TT can be diagnosed easily by DWI without administrating any contrast material. DWI findings in the affected testicle may represent testicular salvageability.

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Year:  2016        PMID: 27690538      PMCID: PMC5604925          DOI: 10.1259/bjr.20160585

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  28 in total

Review 1.  Basic principles of diffusion-weighted imaging.

Authors:  Roland Bammer
Journal:  Eur J Radiol       Date:  2003-03       Impact factor: 3.528

2.  Region of interest demarcation for quantification of the apparent diffusion coefficient in breast lesions and its interobserver variability.

Authors:  Luísa Nogueira; Sofia Brandão; Eduarda Matos; Rita Gouveia Nunes; Hugo Alexandre Ferreira; Joana Loureiro; Isabel Ramos
Journal:  Diagn Interv Radiol       Date:  2015 Mar-Apr       Impact factor: 2.630

3.  Ipsilateral and contralateral testicular biochemical acute changes after unilateral testicular torsion and detorsion.

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Journal:  Urology       Date:  1994-09       Impact factor: 2.649

4.  Diffusion-weighted MR imaging of kidneys in healthy volunteers and patients with parenchymal diseases: initial experience.

Authors:  Harriet C Thoeny; Frederik De Keyzer; Raymond H Oyen; Ronald R Peeters
Journal:  Radiology       Date:  2005-04-21       Impact factor: 11.105

5.  Scrotal disorders: evaluation of testicular enhancement patterns at dynamic contrast-enhanced subtraction MR imaging.

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Journal:  Radiology       Date:  2000-10       Impact factor: 11.105

6.  Bilateral simultaneous testicular torsion presenting as a diagnostic dilemma.

Authors:  Andrei M Beliaev; Ian Mundy
Journal:  BMJ Case Rep       Date:  2013-05-22

7.  Testicular torsion in infants and children: diagnosis with Doppler sonography.

Authors:  H B Patriquin; S Yazbeck; B Trinh; S Jéquier; P N Burns; A Grignon; D Filiatrault; L Garel; J Dubois
Journal:  Radiology       Date:  1993-09       Impact factor: 11.105

8.  The normal and abnormal scrotum in children: evaluation with color Doppler sonography.

Authors:  G O Atkinson; L E Patrick; T I Ball; C A Stephenson; B H Broecker; J R Woodard
Journal:  AJR Am J Roentgenol       Date:  1992-03       Impact factor: 3.959

9.  Parenchymal echo texture predicts testicular salvage after torsion: potential impact on the need for emergent exploration.

Authors:  Jonathan D Kaye; Edan Y Shapiro; Selwyn B Levitt; Steven C Friedman; Jordan Gitlin; Jaime Freyle; Lane S Palmer
Journal:  J Urol       Date:  2008-08-21       Impact factor: 7.450

10.  Tumour ADC measurements in rectal cancer: effect of ROI methods on ADC values and interobserver variability.

Authors:  Doenja M J Lambregts; Geerard L Beets; Monique Maas; Luís Curvo-Semedo; Alfons G H Kessels; Thomas Thywissen; Regina G H Beets-Tan
Journal:  Eur Radiol       Date:  2011-08-07       Impact factor: 5.315

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  1 in total

1.  Diffusion-Weighted Imaging and Color Doppler Ultrasound in Evaluation of Partial Testicular Torsion in Rat Model.

Authors:  Furkan Ufuk; Duygu Herek; Özkan Herek; Metin Akbulut
Journal:  Pol J Radiol       Date:  2017-09-15
  1 in total

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