Literature DB >> 27690183

Bacterial Hyaluronidase Self-Triggered Prodrug Release for Chemo-Photothermal Synergistic Treatment of Bacterial Infection.

Haiwei Ji1,2, Kai Dong1, Zhengqin Yan1,2, Chao Ding1,2, Zhaowei Chen1,2, Jinsong Ren1, Xiaogang Qu1.   

Abstract

A novel platform for targeted on-demand prodrug ascorbic acid (AA) delivery is fabricated using a bacterial hyaluronidase sensitive graphene-mesoporous silica nanosheet@hyaluronic acid-magnetic nanoparticles as the nanocarrier to treat bacterial infections. The released AA can be converted to detrimental •OH in situ on the surface of bacteria. With the chemo-photothermal synergistic effect, the designed antibacterial system can effectively inactivate bacteria and disperse stubborn biofilm.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  antibacterial system; drug delivery; hyaluronic acid; on-demand; reactive oxygen species

Mesh：

Substances：

Year:  2016        PMID： 27690183     DOI： 10.1002/smll.201601729

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  23 in total

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Review 2.  Antibacterial biomaterials for skin wound dressing.

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Journal:  Asian J Pharm Sci       Date:  2022-01-24       Impact factor: 9.273

3.  Soft Materials that Intercept, Respond to, and Sequester Bacterial Siderophores.

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Review 4.  Plasmonic nano-antimicrobials: properties, mechanisms and applications in microbe inactivation and sensing.

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Journal:  Nanoscale       Date:  2021-02-04       Impact factor: 7.790

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6.  CuS@Corn Stalk/Chitin Composite Hydrogel for Photodegradation and Antibacterial.

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Review 7.  A Review on Metal- and Metal Oxide-Based Nanozymes: Properties, Mechanisms, and Applications.

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Journal:  Nanomicro Lett       Date:  2021-07-09

8.  An efficient antimicrobial depot for infectious site-targeted chemo-photothermal therapy.

Authors:  Menglong Liu; Danfeng He; Tao Yang; Wei Liu; Li Mao; Yang Zhu; Jun Wu; Gaoxing Luo; Jun Deng
Journal:  J Nanobiotechnology       Date:  2018-03-16       Impact factor: 10.435

9.  Bacteria responsive polyoxometalates nanocluster strategy to regulate biofilm microenvironments for enhanced synergetic antibiofilm activity and wound healing.

Authors:  Yuetong Zhang; Yang Pi; Yusheng Hua; Jiani Xie; Chengyan Wang; Kun Guo; Zhigang Zhao; Yuan Yong
Journal:  Theranostics       Date:  2020-08-08       Impact factor: 11.556

10.  Highly Effective and Noninvasive Near-Infrared Eradication of a Staphylococcus aureus Biofilm on Implants by a Photoresponsive Coating within 20 Min.

Authors:  Mu Li; Liqian Li; Kun Su; Xiangmei Liu; Tianjin Zhang; Yanqin Liang; Doudou Jing; Xianjin Yang; Dong Zheng; Zhenduo Cui; Zhaoyang Li; Shengli Zhu; Kelvin Wai Kwok Yeung; Yufeng Zheng; Xianbao Wang; Shuilin Wu
Journal:  Adv Sci (Weinh)       Date:  2019-07-19       Impact factor: 16.806
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