Literature DB >> 27687486

Small molecule induces Wnt asymmetry in cancer.

Yi Qu1,2, Karl-Henning Kalland1,2,3, Xisong Ke1.   

Abstract

Entities:  

Keywords:  Axitinib; SHPRH; Wnt signaling; asymmetric cell division; β-catenin

Mesh：

Substances：

Year:  2016        PMID： 27687486      PMCID： PMC5283811          DOI： 10.1080/15384101.2016.1235850

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  Wnt signalling in stem cells and cancer.

Authors:  Tannishtha Reya; Hans Clevers
Journal:  Nature       Date:  2005-04-14       Impact factor: 49.962

Review 2.  Network pharmacology: the next paradigm in drug discovery.

Authors:  Andrew L Hopkins
Journal:  Nat Chem Biol       Date:  2008-11       Impact factor: 15.040

3.  Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.

Authors:  Aaron J Quyn; Paul L Appleton; Francis A Carey; Robert J C Steele; Nick Barker; Hans Clevers; Rachel A Ridgway; Owen J Sansom; Inke S Näthke
Journal:  Cell Stem Cell       Date:  2010-02-05       Impact factor: 24.633

4.  Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer.

Authors:  Yi Qu; Naouel Gharbi; Xing Yuan; Jan Roger Olsen; Pernille Blicher; Bjørn Dalhus; Karl A Brokstad; Biaoyang Lin; Anne Margrete Øyan; Weidong Zhang; Karl-Henning Kalland; Xisong Ke
Journal:  Proc Natl Acad Sci U S A       Date:  2016-08-01       Impact factor: 11.205

Review 5.  Fearful symmetry: subversion of asymmetric division in cancer development and progression.

Authors:  Jeevisha Bajaj; Bryan Zimdahl; Tannishtha Reya
Journal:  Cancer Res       Date:  2015-02-13       Impact factor: 12.701

6.  Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

Authors:  Dana D Hu-Lowe; Helen Y Zou; Maren L Grazzini; Max E Hallin; Grant R Wickman; Karin Amundson; Jeffrey H Chen; David A Rewolinski; Shinji Yamazaki; Ellen Y Wu; Michele A McTigue; Brion W Murray; Robert S Kania; Patrick O'Connor; David R Shalinsky; Steve L Bender
Journal:  Clin Cancer Res       Date:  2008-11-15       Impact factor: 12.531

7.  High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny.

Authors:  Michael J Conboy; Ariela O Karasov; Thomas A Rando
Journal:  PLoS Biol       Date:  2007-05       Impact factor: 8.029
  7 in total
  1 in total

1.  Lidocaine inhibits the proliferation and metastasis of epithelial ovarian cancer through the Wnt/β-catenin pathway.

Authors:  Mei Sun; Saisai Huang; Yongtao Gao
Journal:  Transl Cancer Res       Date:  2021-07       Impact factor: 1.241
  1 in total

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